What is the key factor in septic shock that often leads to organ failure and high mortality rates? Excessive production of anti-inflammatory molecules Activation of blood clotting Release of anti-inflammatory cytokines Excessive production of antibodies
Added by Montserrat Z.
Close
Step 1
Step 1: Septic shock is a life-threatening condition caused by the body's overwhelming and uncontrolled response to infection. Show more…
Show all steps
Your feedback will help us improve your experience
Sri K and 60 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
A 33-year-old male presents in the ER with sepsis, fever, rash, and low blood pressure (signs of septic shock). A blood sample revealed the presence of Gram-negative bacteria upon rapid culture. He is subsequently given a bactericidal antibiotic which worsened his condition. He later expired from what appeared to be multiple organ failure. Which one of the following provides the best explanation for the clinical outcome following treatment? A. The antibiotic agent impaired the immune response. B. The killed bacteria released high levels of endotoxin into the blood. C. The antibiotic impaired bacterial growth, generating cells. D. The antibiotic inhibited cytokine production in the intestinal lumen tissue (extracellular connective tissue).
Sri K.
If a gram-negative bacterial infection reaches the bloodstream, large quantities of LPS can be released into the blood, resulting in a syndrome called septic shock. Death due to septic shock is a real danger. The overwhelming immune and inflammatory responses that occur with septic shock can cause a perilous drop in blood pressure; intravascular blood clotting; development of thrombi and emboli that block blood vessels, leading to tissue death; failure of multiple organs; and death of the patient. Identify and characterize two to three therapies that might be useful in stopping the dangerous events and outcomes of septic shock once it has begun, given what you have learned about inflammation and innate immunity in this chapter.
All but one of the following occur during the inflammatory response. Select the example below that does not describe the process of inflammation A) Increases capillary permeability B) Release of prostaglandins resulting in pain: C) Chemotaxis draws leukocytes to the site of injury: D) Vasoconstriction will prevent excessive blood loss due to injury: 27) Membrane attack complex (MAC) kills bacteria by A) allowing the organelles to spill free from the bacterial cells B) penetrating the capsule of the bacteria and entering the bacterial cytosol, providing passage for antibodies to enter the bacteria plasma membrane C) disrupting the selectively permeability of the bacterial cytoplasmic membrane D) preventing the replication of viral cells 28) Interferons produced against one specific virus A) are effective against another virus, such as the common cold B) are routinely used in nasal sprays to increase the rate of cell division C) act by increasing replication within cells to interfere with viral replication
Madhur L.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD