What is thought to maintain X chromosome inactivation? A Option A: both repressive histone modifications and DNA methylation B Option B: RNA inactivation C Option C: localized DNA denaturation D Option D: DNA methylation E Option E: repressive histone modifications
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This process is thought to be maintained by a combination of mechanisms, including repressive histone modifications and DNA methylation. Repressive histone modifications, such as histone H3 lysine 9 methylation (H3K9me) and histone H3 lysine 27 methylation Show more…
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During mitosis, chromatin is highly condensed. This tightly packed structure is maintained by inhibition of DNA replication and gene transcription, increasing the number of histone proteins in nucleosomes, and decreasing the number of histone proteins in nucleosomes. In addition, there is inactivation of many of the chromatin-remodeling complexes, as well as specific chemical modifications of the histones. Which of the following statements is not correct about X chromosome inactivation in mammal females? The two X chromosomes in females have equal chances to be inactivated. The inactivation of the X chromosome is constitutive. Inactivation of the X chromosome is to maintain gene dosage equivalence between male and female. The inactivated X chromosome is called the Barr body.
Mj A.
Which of the following is an example of an epigenetic change that alters gene expression? a. chromatin remodeling b. covalent histone modification c. localization of histone variants d. DNA methylation e. all of the above
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