What statement about antibodies is false a antibodies are...

What statement about antibodies is FALSE? A. Antibodies are composed of 2 heavy chains and 2 light chains. B. Disulfide bonds link the heavy and light chains together. C. An F(ab')2 fragment would elute before an Fab fragment (aka - have a shorter retention time) on a size exclusion column. D. A monomeric antibody can bind to only one antigenic determinant at a time. E. The hinge region of antibodies improves the efficiency of antigen binding.

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Transcript

00:01 Hi, in the question we are given five statements and we have to find out which one of the following statement is false regarding antibodies.

00:09 Okay, regarding antibodies.

00:11 So first let's see the structure of antibody.

00:15 Okay.

00:16 So it is a y -shaped structure.

00:19 The antibody is a y -shaped.

00:21 Okay.

00:25 It is, uh, okay.

00:30 This is, these two are light chains.

00:33 Okay and these two are heavy chains okay and it is bind it is linked together with disulfide bonds this is disulfide bonds okay these both chains are linked together with disulfide bonds and this particular site right this particular region is the antigen binding site it is the binding site okay and this is the variable region and this is the constant region constant region okay so if we take this part okay if we take this part it is the fab dash 2 region and if we take only this part without the hinge region then this is f, a, b region.

01:31 Okay.

01:32 So this is the basic structure.

01:35 Let's see the options and find out which one of the following is false.

01:39 Okay.

01:40 So the first option is, a option is, antibody are composed of two light chains and two heavy chains.

01:48 Yeah, this is true.

01:49 We have one, this is one light chain and second light chain, one heavy chain and second light chain...