00:01
What would happen if adenine could pair with all of the other bases? what would be the implications here? so let's start with what actually happens.
00:09
So in reality, adenine binds to thymine, cytosine binds to guine.
00:15
Which means that when you want to replicate dna, you of course separate it into two separate strands.
00:21
So let's see you have this strand here.
00:24
Let's say that this is the sequence.
00:31
When you synthesize the new strands, you know exactly what sequence it has to be, because it's complementary.
00:39
You know that the adenine will be a thymine, the cytosine will be a guanine, the thymine will be an adenine, the guanine will be cytosine, and this will again be a thymine.
00:49
So that's great, because now this molecule, in future, when this is replicated, when these separate, the information is conserved.
00:59
Given one strand, and you always know what the other one will be.
01:04
So information is conserved, even when the strands are separated.
01:10
Now, let's look at this particular case.
01:13
What if adenine could pair with anything else? well, let's get rid of this, and let's try to replicate this strand again.
01:21
Adonine.
01:22
It could be anything.
01:23
We don't know what goes here.
01:25
Citazine, it could be guanin, or it could be adenine.
01:29
Biamin, well, actually that one's just going to be adenine.
01:34
Guanine, it could be cytotene, could be adenine, adenine, it could be anything.
01:39
So now you see that we're going to get a mismatch here.
01:45
And in the second round of replication, when this cell is dividing again and these strands are separating, this is going to give us a completely different results to this.
01:55
We're not going to have the information conserved.
01:58
So the implication for dna replication is it will no longer be accurate...