When an action potential arrives at the end of the axon terminal, a series of events take place that result in the release of neurotransmitter from the presynaptic axon. Select the answer that correctly describes the primary stimulus for
vesicles to move toward the cell membrane and eventually release their contents.
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Voltage-gated channels open, and K+ exits to the extracellular fluid, decreasing intracellular K+.
Voltage-gated membrane channels open, and multiple types of ions enter the cytoplasm, increasing the intracellular positive charge.
Axonal Ca+2 is increased because endoplasmic reticulum voltage-gated calcium channels open and Ca*2 enters the cytoplasm.
Voltage-gated membrane channels open, and Ca*2 enters the cytoplasm, increasing intracellular calcium.