Which of the following about CDK and cyclins during the cell cycle is correct? The amount of various cyclin proteins changes at different stages of the cell cycle Cyclin proteins are kinases that can directly phosphorylate the CDK protein. The amount of the CDK (cyclin-dependent kinase) changes at different stages of the cell cycle. For all cyclin-CDK complexes, binding of the cyclin to the CDK is sufficient for full activation of the cyclin-CDK complex.
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Step 1: Cyclin proteins are regulatory subunits of the enzymes called cyclin-dependent kinases (CDKs). Show more…
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Which of the following is false about cyclin-cdk complexes? A. Cdks do not have to bind to cyclin proteins for the complex to be active. B. Cdk/cyclin complexes phosphorylate proteins required to trigger the next cell cycle phase. C. Cyclin concentrations increase gradually, but cdk must be phosphorylated by a specific kinase for the complex to be active. D. The process acts as molecular brakes to ensure the cell is ready to continue with the cell cycle.
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Which statement about cyclin-dependent kinases (CDKs) or cyclin is true? Cyclin is made continuously during the cell cycle. Phosphorylated retinoblastoma protein is active. CDKs are only present during M phase of the cell cycle. G1 cyclin binds to S cyclin, producing an active kinase that is functional during G1. A CDK bound to a G1/S cyclin can catalyze the phosphorylation of retinoblastoma protein.
Which of the following statements are correct? Explain your answers. A. Centrosomes are replicated before $\mathrm{M}$ phase begins. B. Two sister chromatids arise by replication of the DNA of the same chromosome and remain paired as they line up on the metaphase plate. C. Interpolar microtubules attach end-to-end and are therefore continuous from one spindle pole to the other. D. Microtubule polymerization and depolymerization and microtubule motor proteins are all required for DNA replication. E. Microtubules nucleate at the centromeres and then connect to the kinetochores, which are structures at the centrosome regions of chromosomes.
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