Which of the following best describes the hypothesis tested in the paper? Group of answer choices: Changing the sgRNA of the SpCas9-sgRNA complex increases the fidelity of the entire complex. The SpCas9-sgRNA complex specifically binds to the PAM sequence (protospacer adjacent motif). The SpCas9-sgRNA complex makes off-target edits. Disruption of one or more of the amino acid residues that contact DNA alters the energetics of the SpCas9-sgRNA complex so that it has diminished ability to cleave off-target sites.
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Which of the following is a hypothesis regarding the origins of primates? Group of answer choices The change in climate caused a reduction in forests, so the mammals that could adapt to terrestrial living became primates. The radiation of flowering plants changed the composition of forests and resulted in new mammals (primates) that could exploit these new plants. Primates evolved their features to be better hunters of meat. None of the above
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