Which of the following is a good reason for a couple to receive genetic counseling before they plan a pregnancy? They have diverse ethnic backgrounds. The woman is under 30. They have relatives with serious genetic disorders. They have a history of high fertility. Question 11 The chromosome pair in humans that determines sex is the 23rd pair. False True
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Which of the following are typical reasons why individuals or couples may seek genetic counseling? (Select all that apply.) A. A couple has given birth to a child with a genetic disease. B. A couple experiences difficulties in achieving a successful pregnancy. C. A husband is 15 years older than his wife and they wish to have children. D. A person knows of a genetic disease in the family. E. A husband and wife are closely related and they wish to have children.
Madhur L.
A couple planning their family are aware that through the past three generations on the husband's side a substantial number of stillbirths have occurred. The wife has studied genetics and urges her husband to visit a genetic counseling clinic, where a complete karyotype-banding analysis is performed. The tests show that he has the correct number of chromosomes (see below) A) What is the fathers chromosomal abnormality? B) Why can the father be normal with such a large chromosomal abnormality?
Question 8. Adventures of a genetics counselor: A. A couple comes to you for genetic counseling. Both of them have a genetic disorder, but they already have one child who does not have the disorder. They want to have more children and were told by a friend that since their first child was normal all of their future children would be normal as well. Explain to them the probability of future offspring being normal or having the disease (assume that this is an autosomal disease). Be sure to tell them whether the disease is brought about by a dominant or recessive allele and what fraction of their children (if any) could be carriers for the disease. B. Suppose a couple has come to see you to discuss the probability of their children having cystic fibrosis (CF). CF is known to be an autosomal recessive disease caused by a single gene mutation that has pleiotropic effects including thick mucus in the lungs and excessively salty sweat. After discussion with the couple, you learn that they both have a history of the disease in their families. Both the man and his wife are phenotypically normal, but both have one parent and one sibling with CF. The other parent in each case is phenotypically normal. Explain to the couple the probability of their children having CF or being carriers for the CF gene. Explain to them why their children can have the disease even though neither of them have the disease. Draw a Punnett square to help illustrate your points. C. You face a situation with a couple who comes into your office to discuss potential color blindness in their children. The man is not color blind, but his wife is. They already have one daughter who is color blind and want to know the probability of future children having the disorder. First, you will need to explain to the couple the difference between sex chromosomes and autosomal chromosomes, and that color blindness is caused by a recessive mutation in a gene found on the X chromosome. Once they understand this, you can explain to them the probability of their offspring (male and female) having the disorder. You should thus also be able to identify a more immediate and unsettling dilemma for this couple.
Shaiju T.
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