00:01
Hello students, so true this question is about which of the following statement is not true.
00:06
So out of the given statements, the statement which is incorrect is going to be our answer.
00:11
So first is dna methylation inhibits the gene expression.
00:15
So this is a true statement.
00:17
So it is not our answer because true statement is incorrect answer.
00:22
So dna methylation and dna acetylations are the gene regulation events.
00:29
So dna methylation usually inhibit the transcription, which means that our gene will be turned off.
00:39
Turned off and dna acetylation will turn on the gene.
00:48
So gene will be turned on.
00:50
So now next is housekeeping genes are unmithylated and they are active.
00:58
So this is a true statement and hence we can eliminate it.
01:02
So housekeeping genes are those genes which are keeping our cell active, which are keeping our cell active.
01:13
So they contain the cpg islands.
01:16
Cpg islands means that there is more proportion of cytosine and guanine and they are generally not methylated.
01:25
So if they are methylated, so suppose that they are methylated, which means that their gene will be off.
01:31
But we need to keep them active.
01:33
So obviously they are not methylated.
01:35
They are not methylated.
01:37
Methylated means that addition of methyl group.
01:40
Addition of methyl group turn off the gene.
01:44
Turn off the tf2d to bind to the tata box of the promoter.
01:53
So this is a true.
01:54
This is a true statement and hence we can eliminate.
01:57
So during transcription what happens? what happens.
02:02
So if this is the tata box, tata box, we know that number of transcription factor come.
02:09
Transcription factors come and out of them tf2d binds to it.
02:14
So if tf2d binds and after that other transcription factor will bind and rna polymerase will be brought.
02:21
So if tf2d will be repressed by some kind of repressor protein.
02:27
Repressor protein means that it is affecting the tf2d.
02:31
It is affecting the tf2d.
02:33
So tf2d will not be able to not be able to bind to tata box...