00:01
Which of these is not a histone modification? acetylation, methyllation, phosphorylation, glycosylation, or both phosphorylation and glycoslation.
00:11
Okay, we'll start with by saying what we're adding here, or taking away.
00:16
So, in all these cases, we are adding something to the histones, possibly.
00:21
There's acetylation, which is the addition of an acetyl group, which is a ch3co group, so you have the little methyl bit, and you also have a carbon double bonded to an oxygen.
00:33
So it looks like this.
00:38
And this bit adds on to the protein.
00:41
So that is one option.
00:45
So now get smaller, put it over here.
00:49
So that's acetylation.
00:51
Next we have methylation.
00:53
So this is the addition of a methyl group.
00:56
So a methyl group is just ch3.
01:00
So i'll put this for the...
01:03
So the addition of a methyl group.
01:04
Then we have phosphorylation, which is the addition of a phosphate group.
01:12
So, so, p .o .3 is added...