Which of the following is true about the role of B cells in immunological tolerance? Multiple Choice A.) The deletion of self-reactive B cells takes place in primary lymphoid tissue. B.) B cells recognize self antigens in conjunction with MHC molecules in these processes. C.) Immunologic tolerance is often maintained only within the T-cell population, sustaining tolerance because it denies the help essential for antibody production by self-reactive B cells. D.) For those self antigens present at relatively low concentrations, immunologic tolerance is often maintained only within the B-cell population.
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) The deletion of self-reactive B cells does indeed take place in primary lymphoid tissue, specifically in the bone marrow. This is a process known as clonal deletion, which is a mechanism by which self-reactive lymphocytes are eliminated to prevent autoimmune Show more…
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