Which of the following laboratory results indicates myelosuppression? A. Hemoglobin level 10.5 g/dL B. Absolute neutrophil count 7,500/mm3 C. White blood cells 9,000/mm3 D. Platelet count 11,000/mm3
Added by James O.
Close
Step 1
Myelosuppression is a condition in which bone marrow activity is decreased, resulting in fewer red blood cells, white blood cells, and platelets. It's a common side effect of chemotherapy and radiation therapy. Show more…
Show all steps
Your feedback will help us improve your experience
Adi S and 91 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Consider the following chart of laboratory test results of four patients (A, B, C, and D) Red cell count Hemoglobin Hematocrit White cell count Platelet count Patient A 10 million / mm3 20 g 64% 7000 / mm3 300,000 / mm3 Patient B 4.8 million / mm3 15 g 45% 7500 / mm3 150,000 / mm3 Patient C 3.2 million / mm3 8.2 g 34% 6500 / mm3 350,000 / mm3 Patient D 5.1 million / mm3 14.2 g 48% 15,200 / mm3 300,000 / mm3
Adi S.
4) A 59-year-old female has presented clinically with the following: - Weight loss and night sweats - Splenomegaly - Pallor and dyspnoea - Bruising - Complaints of occasional blurry vision Her clinician ordered a full blood count and a general chemistry profile. The following flagged results were returned: Parameter | Result | Reference Range Haemoglobin (Hb) | 94 g/L | 115-160 g/L Red cell count (RCC) | 3.54 x 10^12/L | 3.8-5.2 x 10^12/L Platelets (PLT) | 525 x 10^9/L | 140-400 x 10^9/L White cell count (WCC) | 151.4 x 10^9/L | 4.0-11.0 x 10^9/L Neutrophil count (Neut) | 53 % 80.2 x 10^9/L | 2.0-8.0 x 10^9/L Lymphocyte count (Lymph) | 2 % 3.0 x 10^9/L | 1.0-4.0 x 10^9/L Monocyte count (Mono) | 2 % 3.0 x 10^9/L | 0.1-1.0 x 10^9/L Eosinophil count (Eos) | 6 % 9.0 x 10^9/L | <0.6 x 10^9/L Basophil Count (Baso) | 3 % 4.5 x 10^9/L | <0.2 x 10^9/L Metamyelocytes | 15 % 22.7 x 10^9/L | Myelocytes | 14 % 21.2 x 10^9/L | Promyelocytes | 3 % 4.5 x 10^9/L | Blasts | 2 % 3.0 x 10^9/L | Nucleated RBC (NRBC) | 2 Per 100/WCC | Morphology | Leucocytosis with a full spectrum of immature and mature myeloid cells. Myeloid cells have normal morphology. Red blood cells are normochromic and normocytic. | Neutrophil alkaline phosphatase score | Markedly decreased | Uric acid (Urate) | 0.59 mmol/L | 0.15 - 0.40 mmol/L Lactate dehydrogenase (LDH) | 646 U/L | 120 - 250 U/L From these results, her clinician requested a bone marrow biopsy for chromosomal analysis. a) Given the results indicate above, what type of leukaemia would you expect this patient to have? b) What abnormality/result would you expect cytogenetic analysis to show and what specific type of chromosomal alteration is this?
Supreeta N.
Look at the CBC chart for an adult male below and use it to answer the following questions: Test Result Units Normal Range (F/M) RBC 4.5 M/̀µL 4.20-5.4 / 4.7-6.1 Hb 11.0 g/dL 12.0-15.5 / 13.5-17.5 HCT 35.0 % 34.9-44.5 / 38.8-50.0 MCV 70 fL 80-100 RDW 12.0 % 11.5-15.5 WBC 5.9 K/µL 3.5-10.5 Neu 1.9 K/µL 1.8-7.8 Lymph 4.0 K/µL 0.7-4.5 Mono 0.3 K/µL 0.1-1.0 Eos 0.2 K/µL 0.0-0.4 Baso 0.1 K/µL 0.0-0.2 Plt 240 K/µL 150-450 10. Which value(s) are abnormal? a. Number of red blood cells b. Number of white blood cells c. Average size of red blood cells d. Number of platelets e. Number of neutrophils 11. Which of the following conditions does this patient show evidence of? a. Viral or bacterial infection b. Polycythemia c. Iron-deficient Anemia d. Aplastic anemia e. None; patient is healthy
Bryan V.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD