00:01
So this is problem number 7 from chapter 17.
00:05
The question is, which among the following mutations might have harmful effect on an organism? a single base insertion near the start of the coding sequence will cause a frame shift mutation.
00:19
Now, there are different types of mutations.
00:22
There are beneficial mutations and harmful mutations, but in this context, in this question, we are going to speak about harmful ones.
00:31
Because the question is, which of the following might have harmful effect? which of the following mutations might have harmful effect for the organism? so, this, which we should see which one of the following might cause a change or alteration in the frame shift.
00:50
Because of the triplet nature of the gene expression by codons, the insertion will alter the reading frame of the sequence.
00:58
There is a change or alteration in the reading frame of the sequence and open reading frame is nothing but the sequence which is transcribed and translated.
01:08
And the change in the reading frame will result in a completely different protein...