Which of the following RNAi targets and cleaves mRNA? a. The guide strand and Argonaute protein b. The passenger strand and Dicer protein c. A complex of endonuclease Pasha with Drosha and double-stranded RNA d. The guide strand and the nuclease Drosha e. The passenger strand, Dicer, and Argonaute proteins One thousand individuals in the state of Chuuk, Micronesia were tested for NF1 mutations. Ten of the 30 mutations in the population were observed in children. What is the mutation rate of NF1 in this population? a. 0.015 per generation b. 0.01 per generation c. 0.05 per generation d. 0.005 per generation e. 0.03 per generation
Added by David L.
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Step 1: The RNAi target that cleaves mRNA is the guide strand and the nuclease Drosha. Show more…
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Compare the mutated strands of DNA to the original template DNA in number one. Template DNA sequence with no mutations: TAC GCA CCG TAT CAT GAT AAT Transcribe the DNA to make an mRNA molecule. Write the correct sequence of bases below: AUG CGU GGC AUA GUA CUA UUA Translate the mRNA to make a strand of amino acids (a protein). Use the table of codons found at the end of the assignment to help you. List the amino acids in order below: The following strand of DNA has a mutation. TAC CCA CCG TAT CAT GAT AAT Transcribe the DNA to make an mRNA molecule. Write the correct sequence of bases below: AUG GGU GGC AUA GUA CUA UUA Translate the mRNA to make a strand of amino acids (a protein). Use the table of codons to help you. List the amino acids in order below: Met - Gly- Gly- Ile - Val- leu - leu Compare this strand of DNA to the DNA in number 1. What type of mutation is this? (Be specific- list all mutation types that apply). How did the mutation change the amino acid sequence?
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