Which of the following statements about a protein in the lumen of the ER is false? (more than one can be selected) A Some of the proteins in the lumen of the ER can end up in the extracellular space. B Some of the proteins in the lumen of the ER can end up in the lumen of an organelle in the endomembrane system. C A protein in the lumen of the ER is synthesized by ribosomes on the ER membrane. D Some of the proteins in the lumen of the ER can end up in the cytosol E Some of the proteins in the lumen of the ER can end up in the plasma membrane.
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Step 1: Proteins in the lumen of the ER are synthesized by ribosomes on the ER membrane. Show more…
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Which of the following statements about the ER is FALSE? Proteins to be delivered to the ER lumen are synthesized on smooth ER. The ER is the major site for new membrane synthesis in the cell. Secreted proteins are first targeted to the ER. The ER membrane is continuous with the outer nuclear membrane.
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Which of the following statements are correct? Explain your answers. A. Ribosomes are cytoplasmic structures that, during protein synthesis, become linked by an mRNA molecule to form polyribosomes. B. The amino acid sequence Leu-His-Arg-Leu-Asp-Ala-GInSer-Lys-Leu-Ser-Ser is a signal sequence that directs proteins to the ER. C. All transport vesicles in the cell must have a v-SNARE protein in their membrane. D. Transport vesicles deliver proteins and lipids to the cell surface. E. If the delivery of prospective lysosomal proteins from the trans Golgi network to the late endosomes were blocked, Iysosomal proteins would be secreted by the constitutive secretion pathways shown in Figure $15-30$ F. Lysosomes digest only substances that have been taken up by cells by endocytosis. G. N-linked sugar chains are found on glycoproteins that face the cell surface, as well as on glycoproteins that face the lumen of the ER, trans Golgi network, and mitochondria. H. Ribosomes bound to the outer nuclear membrane make proteins that are translocated co-translationally into the membrane.
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