00:01
Okay, i'm going to answer this question, let's talk about dna replication in the leading and in the lagging strand.
00:05
Imagine this is your dna, and here you're going to try replicating your dna, okay? and the helicases are opening the strands in this direction.
00:14
So let's suppose this strand goes from three to five and this strand goes from five to three.
00:18
Remember that dna is antiparral, so if you have this three to five, the new strand is going to be synthesized from five to three.
00:27
Okay, and remember that the enzyme that polymerizes or that does this job is the dna is.
00:31
Dna polymerase 3.
00:34
And this dna polymerase 3 work from 5 to 3.
00:40
In this direction, it is going to polymerize the new strand.
00:43
So it's going to work in this direction.
00:46
As you can see, this dna is going to be, or this daughter -restrand is going to be synthesized in the same direction as the helicases are open in the strand.
00:55
So this is why this strand here is going to be called the leading strand, because of the helicases keep open in the strand, dna polymer is going to continue polymerizing normally in the same direction.
01:08
Okay? also remember that this dna polymerase cannot start its job out of nothing.
01:13
It is going to require a small segment of primers here...