Which of the following statements about rabies is false? • Most infections in the U.S. are the result of bites from infected dogs. • Diagnosis is based on immunofluorescent techniques. • Hydrophobia is associated with the disease. • It is caused by Lyssavirus. • Average incubation period is 30 to 50 days after initial infection.
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Which of the following is FALSE regarding Rhabdoviridae? You can become infected with rabies by coming into contact with the saliva of an infected animal. Lyssavirus is commonly known as rabies. Bats are responsible for most cases in humans. If rabies is left untreated, it has a one hundred percent mortality. There is an effective vaccination and gamma globulin shot for rabies.
Shaiju T.
David's doctor was concerned that his symptoms included prickling and itching at the site of the dog bite; these sensations could be early symptoms of rabies. Several tests are available to diagnose rabies in live patients, but no single antemortem test is adequate. The doctor decided to take samples of David's blood, saliva, and skin for testing. The skin sample was taken from the nape of the neck (posterior side of the neck near the hairline). It was about 6 mm long and contained at least 10 hair follicles, including the superficial cutaneous nerve. An immunofluorescent staining technique was used on the skin biopsy specimen to detect rabies antibodies in the cutaneous nerves at the base of the hair follicles. A test was also performed on a serum sample from David's blood to determine whether any antibodies for the rabies virus had been produced. Meanwhile, the saliva sample was used for reverse transcriptase-polymerase chain reaction (RT-PCR) analysis, a test that can detect the presence of viral nucleic acid (RNA). The blood tests came back positive for the presence of rabies virus antigen, prompting David's doctor to prescribe prophylactic treatment. David is given a series of intramuscular injections of human rabies immunoglobulin along with a series of rabies vaccines. Why does the immunofluorescent technique look for rabies antibodies rather than the rabies virus itself? If David has contracted rabies, what is his prognosis?
Madhur L.
What observation is inconsistent in humans exposed to the rabies virus? A. Rabies symptoms include hydrophobia, aerophobia, confusion, and hallucination. B. To transmit the virus, the animal must be shedding the virus in saliva. C. The virus moves quickly along axons, through the cytoplasm, to the brain. D. Incubation time is proportional to the distance between bite wound and brain.
Sri K.
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