Which of the following statements best describes the reversible phosphorylation of enzymes by protein kinases and phosphatases? a. Both reactions are favorable because a phosphatase catalyzes the reverse reaction of the protein kinase b. The reaction catalyzed by the phosphatase is unfavorable because it is the reverse reaction of the favorable reaction catalyzed by the protein kinase c. The reactions catalyzed by the enzymes are not the reverse of one another, and therefore both can be thermodynamically favorable d. The reaction catalyzed by the phosphatase is favorable because ATP is hydrolyzed during the reaction e. A protein kinase is likely to catalyze the backward reaction under physiological conditions, making a phosphatase unnecessary
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Step 1: The reversible phosphorylation of enzymes involves the addition of a phosphate group by a protein kinase and the removal of the phosphate group by a phosphatase. Show more…
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Question 6 (1 point) Which of the following is TRUE of the kinases and phosphatases controlling the extent of protein phosphorylation in the cell? a) All of the answers are correct. b) Both reactions are virtually irreversible under physiological conditions. c) The reactions catalyzed by protein kinases and protein phosphatases are not the reverse of one another. d) Both reactions take place at negligible rates in the absence of enzymes. e) The rate of cycling between the phosphorylated and the dephosphorylated states depends on the relative activities of kinases and phosphatases.
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When a signal is being transduced in the cell, various types of reverse reactions occur in order to terminate a cellular response in the absence of the signal. Which of the following is involved in such a reverse reaction? a. activation of protein phosphatase b. dephosphorylation of G protein c. phosphorylation of receptor tyrosine kinase d. activation of phospholipase C e. activation of adenylyl cyclase
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Kinases are enzymes that transfer a phosphoryl group from a nucleoside triphosphate. Which of the following are valid kinase-catalyzed reactions? (a) $\mathrm{ADP}+\mathrm{CMP} \rightarrow \mathrm{AMP}+\mathrm{CDP}$ (b) $\mathrm{AMP}+\mathrm{ATP} \rightarrow 2$ ADP
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