Which of the following statements concerning the sequence of events involved in the initiation of transcription by E. coli RNA polymerase are correct? Initiation starts with a purine nucleotide triphosphate, which is destined to become the 5'-end of RNA. RNA polymerase in E. coli is a multimeric protein of the form α2ββ'σ. The double-stranded DNA is split into single-stranded DNA at the Pribnow box, an A:T-rich region. The sigma factor does not dissociate until RNA elongation is complete. RNA polymerase in E. coli is a monomeric protein involved only in the initiation of transcription. Initiation starts with a purine nucleotide triphosphate, which is destined to become the 5'-end of RNA.
Added by Joshua S.
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Step 1: RNA polymerase binds to the DNA double helix at the tata box, which is rich in A and T pairs. Show more…
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