Which of the following statements describes a microarray? Multiple Choice Patient samples are lonized when subjected to metal plates and lasers, and then the ions are separated and identified by their mass-to-charge ratio. MRIs and PET scans are used to find areas in deep tissues where infections are caused by biofilms. Absorbent plates ("chips") are loaded with thousands of potential gene sequences from different organisms, and patient specimens are incubated on the plates, allowing a computer to detect regions where there is a match. Random primers are used to discover novel sequences in the microbe's DNA. Help
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A microarray is a tool used to analyze gene expression. It consists of a solid surface with thousands of DNA probes attached to it. These probes are designed to bind to specific mRNA molecules. When a sample of mRNA is applied to the microarray, the mRNA molecules Show more…
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Which of the following statements does not accurately describe gene microarrays? They are used to compare gene expression patterns between normal and diseased tissues. They are used to study the transcriptome. The intensity of spot fluorescence indicates the relative level of expression. They contain thousands of different spots of protein.
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15. Which of the following is NOT true regarding microarray technology and cancer? A. DNA microarrays are used to measure the expression levels of large number of genes at once (transcriptomics) or to genotype multiple regions of a genome (genomics). B. A DNA microarray can determine the type of cancer (diagnosis). C. A DNA microarray can measure the response of a cancer to therapy (prognosis). D. A DNA microarray can be used to predict whether the cancer will move from one place to another in the body (metastasis). E. DNA microarrays can be used to synthesize RNA interference peptides to treat cancer. 16. Next-generation sequencing ________. A. uses massively parallel technologies to increase throughput B. allowed to sequence the human genome faster than earlier estimates C. relies in the presence of fluorescently labeled terminator nucleotides to produce "reads" of various lengths that are detected with a laser D. A and B are correct E. A and C are correct
The "complementary sequence that is created to identify a particular stretch of DNA" is the: probe primer polymerase hybridization Dr. Brown obtains "intermediate" results from a susceptibility test. She may correctly interpret this to mean that the antimicrobial agent in question: may be successfully used to treat infection caused by the bacterial isolate test is potentially useful if the concentration is high enough cannot be effective against the tested isolate is not appropriate for treating infection caused by this bacterial isolate because the test highly correlates with a resistance mechanism that renders treatment success doubtful 1 and 4 The major advantage of microarrays is that they: allow the analysis of nucleic acids much more rapidly after performance of a Southern blot allow the separation of different fragments of nucleic acids according to their molecular size quantitate DNA synthesis in a sample in real time allow the simultaneous analysis of a very large number of target sequences
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