Which of the following statements is false? A typical XX human female has one Barr body. An individual with Turner Syndrome has no Barr bodies. An individual with Klinefelter syndrome generally has one Barr body. Dosage compensation is accomplished in humans by inactivation of the Y chromosome. In a cell with x chromosomes lacking the XIC, there is still x inactivation.
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Adi S.
Dosage Compensation 1. An individual with Turner Syndrome would be expected to have how many Barr bodies in the majority of cells? 2. An individual who has Klinefelter syndrome (XXY) would be expected to have how many Barr Bodies in the somatic cells? 3. What is a Barr Body? How would you expect the structure of a Barr body to affect X-linked gene expression? 4. Why is dosage compensation necessary?
Humans who have aneuploidy of the sex chromosomes are viable. A female human who has Turner syndrome (XO) has one too few X chromosomes and will produce a normal amount of proteins from genes on autosomes. A person who is XO has one X chromosome. A Barr body will not form. Most X chromosome genes produce a normal amount of protein. The few genes in the PAR region of the X chromosome remain active on all copies of the X chromosome. With Turner syndrome, those genes produce less protein in somatic cells than normal, leading to skeletal abnormalities. The Barr body is normally reactivated. In individuals with Turner syndrome, the lower dose of X chromosome gene expression in the female germ line leads to defective oogenesis and infertility.
Marlyn J.
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