Which of the following statements is not correct about epigenetics and epigenetic mechanisms? Epigenetic mechanisms are heritable changes in DNA sequence, gene expression, and function. These changes include DNA methylation, histone modifications, and non-coding RNAs. Epigenetic changes are most prominent during early development. Epigenetic changes could pass from one generation to the next. The changes in DNA methylation, histone modifications, and non-coding RNAs occur in specific regions of DNA and histones that are closely related to genes. Sexual reproduction produces genetically variable individuals and requires the fusion of germ cells. Sexual reproduction also requires more energy expenditure than asexual reproduction. If a mutation causes a change in the DNA sequence from AGTCCG-3' to TCCGGC-5', the mutated sequence will read 3' AGGCCG-5'. DNA replication occurs in the 5' to 3' direction. The human chromosomes do not determine whether an individual is male or female. The determination of sex is controlled by other factors. Epigenetic mechanisms occur early in life and can also occur during adulthood. Methylation is an epigenetic mechanism that can turn genes on or off. Gene expression depends on the type of epigenetic modifications. All of the above statements are correct.