Which respiratory complexes are proton pumps? How does this help generate enough energy to phosphorylate ADP to ATP? Which respiratory complex has a role in the citric acid cycle? Is it possible to carry out ATP synthesis in the mitochondria without the electron transport chain running? What about the opposite? Would 2,4- DNP cause P/O ratio of NADH and FADH2 to go up or down? How would it effect oxygen consumption? Explain your rationale.
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The respiratory complexes that are proton pumps are Complex I (NADH:ubiquinone oxidoreductase), Complex III (cytochrome bc1 complex), and Complex IV (cytochrome c oxidase). These complexes pump protons from the mitochondrial matrix to the intermembrane space, Show more…
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