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Which small-scale mutation would be most likely to have a catastrophic effect on functioning of a protein? deletion of three nucleotides (or bases) near the start of the coding sequence but before the initiator codon, AUG a nucleotide insertion within the first intron a base substitution near the end of the coding sequence. a nucleotide deletion within the first exon Question 27 (1 point) Here is a segment of an mRNA (in bold capitals starting with nucleotide 1) and its corresponding protein segment above The original DNA experiences a mutation, such that the resulting mRNA has an A instead of G at position 5. At the protein level, what kind of mutation is this? Met Gly Val Lys Thr Leu Ser 5' A U G G G C G U U A A G A C A U U A A G C U G A U C 3'

          Which small-scale mutation would be most likely to have a catastrophic effect on functioning of a protein?
deletion of three nucleotides (or bases) near the start of the coding sequence but before the initiator codon, AUG
a nucleotide insertion within the first intron
a base substitution near the end of the coding sequence.
a nucleotide deletion within the first exon
Question 27 (1 point)
Here is a segment of an mRNA (in bold capitals starting with nucleotide 1) and its corresponding protein segment above
The original DNA experiences a mutation, such that the resulting mRNA has an A instead of G at position 5. At the protein level, what kind of mutation is this?
Met Gly Val Lys Thr Leu Ser
5' A U G G G C G U U A A G A C A U U A A G C U G A U C 3'

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Which small-scale mutation would be most likely to have a catastrophic effect on functioning of a protein?
deletion of three nucleotides (or bases) near the start of the coding sequence but before the initiator codon, AUG
a nucleotide insertion within the first intron
a base substitution near the end of the coding sequence.
a nucleotide deletion within the first exon
Question 27 (1 point)
Here is a segment of an mRNA (in bold capitals starting with nucleotide 1) and its corresponding protein segment above
The original DNA experiences a mutation, such that the resulting mRNA has an A instead of G at position 5. At the protein level, what kind of mutation is this?
Met Gly Val Lys Thr Leu Ser
5' A U G G G C G U U A A G A C A U U A A G C U G A U C 3'

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Biology for AP Courses

Julianne Zedalis, John Eggebrecht

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Solved by Expert Adi S

11/30/2022

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Deletion of three nucleotides near the start of the coding sequence but before the initiator codon: This mutation is unlikely to have a catastrophic effect on the functioning of a protein. This is because the mutation occurs before the initiator codon (AUG), which Show more…

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Which small-scale mutation would be most likely to have a catastrophic effect on functioning of a protein? deletion of three nucleotides (or bases) near the start of the coding sequence but before the initiator codon, AUG a nucleotide insertion within the first intron a base substitution near the end of the coding sequence. a nucleotide deletion within the first exon Question 27 (1 point) Here is a segment of an mRNA (in bold capitals starting with nucleotide 1) and its corresponding protein segment above The original DNA experiences a mutation, such that the resulting mRNA has an A instead of G at position 5. At the protein level, what kind of mutation is this? Met Gly Val Lys Thr Leu Ser 5' A U G G G C G U U A A G A C A U U A A G C U G A U C 3'

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00:01 Here, in this question, we will be talking about the catastrophic effect.

00:08 Now, what is a catastrophic effect? it is a effect that can cause a sudden but a terrible change.

00:25 Now, look at the options.

00:28 What is written? first, it is written that the deletion of the.

00:32 Three nucleotides near the start of the coding sequence.

00:37 So here first we have to know what is a translation machinery.

00:43 In the translation process, we can see the mrna is ready to synthesizing the protein.

00:52 And for synthesizing the protein, the first codon that will come is the aug.

00:59 So this is the start coden and it will coat for the amino acid methenyne.

01:08 So if the initiation coden has the problem then the whole structure will be affected but in the question it is said that a small scale of nutrition is seen.

01:22 So we can say that option a cannot be the answer.

01:26 Now have a look on the option b.

01:29 It is written nucleotivate.

01:30 Insertion within the first intron.

01:33 Now, when a protein synthesis is taking place, we can see there are some intron and there are some exon.

01:42 This introns are the inactive part that will be go out after the post -translational modification...

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