X Inactivation is controlled by Multiple Choice the SRY gene the XTASY gene the XIST gene the location of the spindle in mitosis
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X inactivation is a process in female mammals where one of the two X chromosomes is silenced. Show more…
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What gene is most responsible for X-inactivation? Multiple Choice Xist Xce Xic Tsix
Adi S.
Keemin L.
Xist gene is located in a 450 kb region of DNA called the X inactivation center (XIC) and is transcribed only from the future inactive X chromosome. The Xist noncoding RNA (ncRNA) triggers X inactivation by coating the X chromosome that produces it and recruiting enzymes that allow Barr body formation. How one X chromosome is chosen to express Xist is unknown. In diploid somatic cells with three X chromosomes (XXX), Xist would be transcribed from [ Select: 0, 1, 2, 3 ] X chromosome(s); in diploid somatic cells with two X chromosomes and one Y (XXY), Xist would be transcribed from [ Select: 0, 1, 2, 3] X chromosome(s). This is because it is essential to maintain the proper dosage of X-linked gene products for cell survival.
Madhur L.
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