You are consulting with a patient and explaining that their medication will be available in a transdermal patch. To ensure that the patient will receive the proper dose, you need to explain why the transdermal patch can be attached anywhere on the skin except the palms of the hands and the soles of the feet. You tell the patient that Palms of the hands and soles of the feet have the thickest stratum basale that will block the medication from being absorbed. These areas have the thinnest skin compared to other areas of the body. All of these should be discussed with the patient. The rate of diffusion of the medication would be extremely fast and its effectiveness increased. Sweating of the palms and soles could result in the patch not adhering and falling off.
Added by Anthony J.
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Many medications can be administered transdermally by applying patches that contain the medication to the surface of the skin. Can these patches be attached anywhere on the skin and be just as effective? A. Yes, it can be attached to any part of the body because it does not matter where the patch is placed. As long as the medication is in the patch, it will be absorbed into the skin, going into the bloodstream, causing it to be effective. B. The patches can be attached anywhere on the skin except the palms of the hands and soles of the feet because both are used too much and would not stick, decreasing the chance for the medicine to enter the body. C. Transdermal medicinal patches are applied through the skin and are absorbed by the bloodstream. They are not placed in the soles of the feet and palms of the hands because the soles and palms have an extra epidermal layer called the stratum lucidum, which is not found anywhere else. This would cause diffusion of transdermal medication to occur slowest at the soles and palms due to an extra epidermal layer.
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