You are in charge of a patient with advanced lung cancer. The patient was intubated with a ventilator (endotracheal tube) to assist with breathing. Ninety-six (96) hours post-intubation, the patient develops pneumonia, an infection in the mucosal tissue. The infectious agent is a Gram-negative species that produces an extended-spectrum beta-lactamase (ESBL). Which of the following apply:
A. The patient is infected with Enterococcus faecalis, VRE, in the blood that produces an altered transpeptidase, can be treated with Zosyn, a "combo drug," and will require tumor necrosis factor alpha secretion for clearance.
B. The patient is infected with Influenza A virus H3N2, that undergoes antigenic shift, can be treated with alpha interferon, and will require mast cell activation with IL-1, IL-6, and IL-8 secretion for clearance.
C. The patient is infected with HA-MRSA in the blood that produces protein A, can be treated with methicillin, and will require IgM for clearance.
D. The patient is infected with Pseudomonas aeruginosa in the dermis that forms attachment pili, can be treated with vancomycin, and will require IgG for clearance.
E. The patient is infected with Klebsiella pneumoniae in the lung that forms a biofilm, can be treated with a carbapenem, and will require IgA for clearance.