Question

You are studying the gene CDKN2, which is on chromosome 9, and you are particularly interested in those with both copies of this gene deleted, which is a recessive loss of function mutation. You perform FISH on 3 samples (A, B & C) with two probes: a green fluorescent probe for another gene on chromosome 9 a red fluorescent probe for CDKN2 The results are shown below. Describe each cell sample in terms of CDKN2: homozygous dominant, homozygous recessive, or heterozygous. Why is the green probe used in this experiment?

          You are studying the gene CDKN2, which is on chromosome 9, and you are particularly interested in those with both copies of this gene deleted, which is a recessive loss of function mutation.
You perform FISH on 3 samples (A, B & C) with two probes:
a green fluorescent probe for another gene on chromosome 9
a red fluorescent probe for CDKN2
The results are shown below. Describe each cell sample in terms of CDKN2: homozygous dominant, homozygous recessive, or heterozygous. 
Why is the green probe used in this experiment?

Added by Julia T.

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