You identify another protein, Protein A, that you propose to function like PHF1 in terms of regulating how PRC2 binds DNA. However, when you perform the TIRF microscopy experiments you see the following data. What can you conclude?
Protein A binds directly to DNA
Protein A is functional but behaves differently to PHF1
Protein A behaves the same as PHF1
Protein A affects both the short-lived state and the long-lived state
Protein A does not affect PRC2 interaction with DNA at all
5. You identify another protein, Protein A, that you propose to function like PHF1 in terms of regulating how PRC2 binds DNA. However, when you perform the TIRF microscopy experiments you see the following data. What can you conclude?
PRC2 PRC2+PHF1 PRC2+Protein A
I counts 8 6 Normalized 4 .2
0
2 3 Time (s)
1
4
Protein A binds directly to DNA
Protein A is functional but behaves differently to PHF1
Protein A behaves the same as PHF1
Protein A affects both the short-lived state and the long-lived state
Protein A does not affect PRC2 interaction with DNA at all