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Zidovudine (AZT) is a drug used to treat patients with acquired immunodeficiency syndrome (AIDS). AZT works by blocking the reverse transcriptase enzyme used by the human immunodeficiency virus (HIV), the causative agent of AIDS. What type of transposable elements would be affected by AZT, and what would be the most likely effect?

          Zidovudine (AZT) is a drug used to treat patients with acquired immunodeficiency syndrome (AIDS). AZT works by blocking the reverse transcriptase enzyme used by the human immunodeficiency virus (HIV), the causative agent of AIDS. What type of transposable elements would be affected by AZT, and what would be the most likely effect?
        
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Biology for AP Courses
Biology for AP Courses
Julianne Zedalis, John Eggebrecht
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Zidovudine (AZT) is a drug used to treat patients with acquired immunodeficiency syndrome (AIDS). AZT works by blocking the reverse transcriptase enzyme used by the human immunodeficiency virus (HIV), the causative agent of AIDS. What type of transposable elements would be affected by AZT, and what would be the most likely effect?
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Transcript

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00:01 All right, so this drug basically is used to treat aids, which is caused by hiv.
00:10 Now, hiv is a virus that is a retrovirus, right? use a reverse transcriptase to create the cdna that will eventually lead to its viral gene products.
00:26 The question is, what type of transmissible elements would be affected, by this drug, a -z -t, or zidovuddin, v -d -vu -d -a -t.
00:40 And what would most likely be the effect? what we're looking for here, the answer is here, is a retro -transposon.
00:58 Okay? because a retro transposeon will excise out via transcription and translation.
01:09 And in the cycle, it will go through reverse transcription.
01:25 Okay? so the results in c -d -n -a, which would then integrate at whatever other point.
01:36 And it would integrate another point in the dna, right? or in another organism.
01:41 But likely in another point in the dna...
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