Objective Biology for NEET

Problem 2

What is indicated by 'b' in the figure?
(a) Base pair end
(b) Only sugar backbone
(c) Only phosphate backbone
(d) Both (b) and (c)

Mishal Gul

Numerade Educator

Problem 3

How many types of nucleic acids are found in living systems?
(a) 3
(b) 1
(c) 2
(d) 4

Mishal Gul

Numerade Educator

Problem 4

Which nucleic acid in some viruses can also act as genetic material?
(a) DNA
(b) RNA
(c) mRNA
(d) tRNA

Mishal Gul

Numerade Educator

Problem 5

The process of making RNA from DNA is termed as
(a) Transaction
(b) Transformation
(c) Transcription
(d) Transduction

Mishal Gul

Numerade Educator

Problem 6

The genetic code
(a) Is a sequence of nucleotides on rRNA.
(b) Determines the sequence of amino acid in proteins.
(c) Is universal in biological systems.
(d) None of the above

Mishal Gul

Numerade Educator

Problem 7

The process of protein synthesis in biological systems is termed as
(a) Transaction
(b) Transcription
(c) Translation
(d) Transformation

Mishal Gul

Numerade Educator

Problem 8

DNA is a polymer of
(a) Nucleotides
(b) Ribonucleotides
(c) Nucleosides
(d) Deoxyribonucleotides

Mishal Gul

Numerade Educator

Problem 9

What is indicated by 'a' in the figure?
(a) $5^{\prime}$ phosphate
(b) $3^{\prime}$ phosphate
(c) Ribose sugar
(d) Nitrogen base

Mishal Gul

Numerade Educator

Problem 10

What is indicated by 'b' in the figure?
(a) $5^{\prime}$ phosphate
(b) $3^{\prime}$ hydroxyl
(c) Ribose sugar
(d) Nitrogen base

Mishal Gul

Numerade Educator

00:15

Problem 11

What does the figure represent?
(a) Polysaccharide
(b) Polynucleoside
(c) Polynucleotide
(d) Polyamine

Mishal Gul

Numerade Educator

Problem 12

The length of DNA is defined in terms of
(a) Number of nucleotides
(b) Base pairs
(c) Both (a) and (b)
(d) $\mu \mathrm{m}$

Mishal Gul

Numerade Educator

Problem 13

A bacteriophage $\varphi \times 174$ has
(a) 5836 base pairs
(b) 5683 nucleotides
(c) 5386 nucleotides
(d) 5638 base pairs

Mishal Gul

Numerade Educator

00:39

Problem 14

Bacteriophage lambda has base pairs in nucleic acid (genetic material).
(a) 48205
(b) 5386
(c) 48502
(d) 45802

Mishal Gul

Numerade Educator

01:32

Which of the following holds true for Escherichia coli?
(a) $E$. coli has roughly 40 minutes of doubling time.
(b) $E$. coli is a parasite in human digestive tract.
(c) $E$. coli has $4.6 \times 10^{9}$ bp long genetic material.
(d) $E$. coli has $4.6 \times 10^{6}$ bp long genetic material.

Mishal Gul

Numerade Educator

01:38

Problem 16

A nucleotide has the following components
(a) A phosphate group, nitrogenous base, a hexose sugar
(b) A phosphorous base, nitrogenous group, a ribose sugar
(c) A nitrogenous base, phosphate group, a ribose sugar
(d) A nitrogenous base, phosphate group, a hexose sugar

Mishal Gul

Numerade Educator

Problem 17

Which of the following is not a pyrimidine?
(a) Thymine
(b) Uracil
(c) Adenine
(d) Cytosine

Mishal Gul

Numerade Educator

Problem 18

What is represented by the figure?
(a) Criminal/Suspect identification
(b) Human genome project
(c) Recombinant DNA technology
(d) Development of Bioinformatics

Mishal Gul

Numerade Educator

Problem 19

is present in DNA only and is present in RNA only
(a) Cytosine, thymine
(b) Thymine, uracil
(c) Uracil, thymine
(d) Thymine, cytosine

Mishal Gul

Numerade Educator

00:50

Problem 20

A nitrogenous base is linked to the pentose sugar through
(a) Phosphoester linkage
(b) O-glycosidic linkage
(c) Phosphodiester linkage
(d) $\mathrm{N}$ -glycosidic linkage

Mishal Gul

Numerade Educator

00:49

Problem 21

In the context of genetic material: Base $+$ Sugar $\rightarrow$
(a) Nucleotide
(b) Nucleoside
(c) Nucleic acid
(d) Nuclein

Mishal Gul

Numerade Educator

00:51

Problem 22

In the context of genetic material, nucleotide consists of
(a) N-base, Ribose sugar, Phosphate group
(b) N-base, Hexose sugar, Phosphate group
(c) Nucleoside + Phosphate
(d) Both (a) and (c)

Mishal Gul

Numerade Educator

Problem 23

Uracil is associated with which sugar?
(a) Generally Deoxyribose
(b) Sometimes Ribose
(c) Only ribose
(d) Hexose

Mishal Gul

Numerade Educator

Problem 24

5 - end of ribose sugar bears
(a) N-base
(b) Deoxyribose
(c) Phosphate group
(d) Hydroxyl group

Mishal Gul

Numerade Educator

Problem 25

3 ' end of the polynucleotide chain bears
(a) Phosphate group
(b) Hydroxyl group
(c) Methyl group
(d) Nitro group

Mishal Gul

Numerade Educator

Problem 26

In RNA, every nucleotide residue has an additional position of ribose
(a) $\mathrm{PO}_{4}^{3-}, 3^{\prime}$
(b) $\mathrm{OH}^{-}, 3$
(c) $\mathrm{OH}^{-}, 2$
(d) $\mathrm{OH}^{-}, 2^{\prime}$

Mishal Gul

Numerade Educator

Problem 27

Thymine can also be designated as
(a) 3 - Methyl uracil
(b) 2 - Methyl uracil
(c) 4 - Methyl uracil
(d) 5 - Methyl Uracil

Mishal Gul

Numerade Educator

01:53

Problem 28

Friedrich Miescher
(a) Identified DNA as a basic substance and named it 'Nucleotide' in 1896 .
(b) Identificd DNA as an acidic substance and named it 'Nuclein' in 1896 .
(c) Identified DNA as an acidic substance and named it 'Nuclein' in 1869 .
(d) None of the above

Mishal Gul

Numerade Educator

Problem 29

What is indicated by ' $\mathrm{m}$ ' in the figure?
(a) y gene
(b) o gene
(c) $\mathrm{z}$ gene
(d) a gene

Mishal Gul

Numerade Educator

00:14

Problem 30

What is indicated by 'r' in the figure?
(a) Suppresor
(b) Operator
(c) Repressor
(d) Inducer

Mishal Gul

Numerade Educator

Problem 31

What is indicated by ' $\mathrm{n}$ ' in the figure?
(a) Induction
(b) Replication
(c) Transcription
(d) Derepression

Mishal Gul

Numerade Educator

Problem 32

What is indicated by ' $\mathrm{q}$ ' in the figure?
(a) Lactase
(b) Transacetylase
(c) $\beta$ -galactosidase
(d) Permease

Mishal Gul

Numerade Educator

01:15

Problem 33

J. D. Watson and F.H. Crick utilized X-ray diffraction data produced by
(a) Rosalind Wilkins and Maurice Franklin
(b) Maurice Wilkins and Rosalind Franklin
(c) Sutton and Boveri
(d) None of these

Mishal Gul

Numerade Educator

01:30

Problem 34

Erwin Chargaff found that
(a) Ratios of adenine and cytosine and thymine and guanine are constant.
(b) Ratios of adenine and thymine and guanine and cytosine are constant.
(c) Ratios of adeninc and guaninc and thyminc and cytosinc are constant.
(d) Ratios of adenine - guanine and thymine - cytosine are constant.

Mishal Gul

Numerade Educator

Problem 35

DNA has two strands which are $\quad$ to each other.
(a) Supplementary
(b) Complementary
(c) Opposite
(d) Perpendicular

Mishal Gul

Numerade Educator

Problem 36

What is indicated by 'a' in the figure?
(a) Extron
(b) Intron
(c) Intein
(d) Exon

Mishal Gul

Numerade Educator

00:22

Problem 37

What does 'b' represent in the figure?
(a) Extron
(b) Intron
(c) Intein
(d) Exon

Mishal Gul

Numerade Educator

Problem 38

The backbone of DNA double helix consists of
(a) Sugar-Base
(b) Sugar-Phosphate
(c) Sugar-Hydroxyl group
(d) Sugar-Methyl group

Mishal Gul

Numerade Educator

Problem 39

Anti-parallel polarity is exhibited by
(a) RNA
(b) $\mathrm{tRNA}$
(c) $\mathrm{mRNA}$
(d) DNA

Mishal Gul

Numerade Educator

00:54

Problem 40

Which of the following holds true in case of DNA?
(a) $\mathrm{A}=\mathrm{T}$
(b) Adenine forms two H-bond with thymine
(c) Adenine forms one $\pi$ bond with thymine
(d) Both (a) and (b)

Mishal Gul

Numerade Educator

Problem 41

Three H-bonds is exhibited by which DNA bases in the double helix structure?
(a) Adenine, Guanine
(b) Guanine, Cytosine
(c) Cytosine, Thymine
(d) Adenine, Thymine

Mishal Gul

Numerade Educator

Problem 42

Double helix model of DNA has a pitch of
(a) $0.34 \mathrm{~nm}$
(b) $3.4 \mathrm{~nm}$
(c) $34 \AA$
(d) Both (b) and (c)

Mishal Gul

Numerade Educator

Problem 43

Double helix model of DNA proposed by Watson and Crick has how many base pairs in one turn?
(a) 9
(b) 11
(c) 12
(d) 10

Mishal Gul

Numerade Educator

01:13

Problem 44

What confers additional stability to double helix modcl of DNA apart from the H-bond?
(a) One base pair provides inductive effect to the other.
(b) One basc pair is stacked over the other.
(c) One base pair is perpendicular to another.
(d) One base pair interacts with another base pair via steric hindrance.

Mishal Gul

Numerade Educator

Problem 45

What is indicated by 'b' in the figure?
(a) Promoter
(b) Terminator
(c) Structural gene
(d) Template strand
(e) Coding strand

Mishal Gul

Numerade Educator

Problem 46

What is indicated by 'e' in the figure?
(a) Terminator
(b) Structural gene
(c) Coding strand
(d) Promoter
(e) Template strand

Mishal Gul

Numerade Educator

Problem 47

What does 'd' represent in the figure?
(a) Template strand
(b) Promoter
(c) Terminator
(d) Structural gene
(e) Coding strand

Mishal Gul

Numerade Educator

Problem 48

What is indicated by 'a' in the figure?
(a) Promoter
(b) Terminator
(c) Structural gene
(d) Template strand
(e) Coding strand

Mishal Gul

Numerade Educator

Problem 49

What does 'c' represent in the figure?
(a) Coding strand
(b) Template strand
(c) Promoter
(d) Terminator
(e) Structural gene

Mishal Gul

Numerade Educator

Problem 50

Central dogma in molecular biology was independently proposed by
(a) Wilkins
(b) Crick
(c) Watson
(d) Franklin

Mishal Gul

Numerade Educator

01:12

Problem 51

The correct representation of central dogma is as follows:
(a) DNA $\stackrel{\text { Transcription }}{\rightarrow}$ mRNA $\underline{\text { Transformation }}{\longrightarrow}$ Protein
Protcins
(b)
Replication
(c) Proteins rem
Replication
(d)

Mishal Gul

Numerade Educator

00:46

Problem 52

Which of the unusual metabolic process is shown by viruses?
(a) DNA to RNA
(b) RNA to DNA
(c) Proteins to RNA
(d) None of these

Mishal Gul

Numerade Educator

Problem 53

RNA $\rightarrow$ DNA is termed as
(a) Reverse translation
(b) Reverse replication
(c) Reverse transcription
(d) Reverse transformation

Mishal Gul

Numerade Educator

01:06

Problem 54

The length of human DNA is approximately
(a) $2.2$ meters considering all cells of body
(b) $3.1$ meters considering only one cell
(c) $2.2$ meters considering only one cell
(d) None of these

Mishal Gul

Numerade Educator

Problem 55

DNA is held together by which proteins in prokaryotes?
(a) Negatively charged proteins
(b) Positively charged proteins
(c) Amphoteric proteins
(d) Histone proteins

Mishal Gul

Numerade Educator

00:58

Problem 56

Which statement is true in the context of histones?
(a) They are positively charged acidic proteins.
(b) They are positively charged amphoteric protein.
(c) They are positively charged basic proteins.
(d) None of the above

Mishal Gul

Numerade Educator

Problem 57

In a nucleosome, histones are organized in which structure?
(a) Octamer
(b) Hexamer
(c) Decamer
(d) Septamer

Mishal Gul

Numerade Educator

00:35

Problem 58

The initial structure formed at the beginning of coiling of DNA around histones is
(a) Nuclein
(b) Solenoid
(c) Nucleosome
(d) Chromatin

Mishal Gul

Numerade Educator

00:38

Problem 59

Histones are rich in which amino acid?
(a) Methionine, Arginine
(b) Lysine, Arginine
(c) Lysinc, Proline
(d) Methionine, Lysine

Mishal Gul

Numerade Educator

Problem 60

Typically a nucleosome consists of how many base pairs?
(a) 190
(b) 200
(c) 300
(d) 310

Mishal Gul

Numerade Educator

Problem 61

Chromatin is made up of
(a) Centromere
(b) Nucleoid
(c) Centrosome
(d) Nucleosome

Mishal Gul

Numerade Educator

Problem 62

Which end of mRNA is shown by 'a' in the figure?
(a) $3^{\prime}$
(b) 3
(c) $5^{\prime}$
(d) 5

Mishal Gul

Numerade Educator

Problem 63

Which end of $\mathrm{mRNA}$ is shown by 'b' in the figure?
(a) $5^{\prime}$
(b) 5
(c) 3
(d) $3^{\prime}$

Mishal Gul

Numerade Educator

00:53

Problem 64

Which amino acid is shown by ' $\mathrm{c}$ ' in the figure?
(a) Aspartic acid
(b) Asparagine
(c) Alanine
(d) Valine

Mishal Gul

Numerade Educator

Problem 65

Which amino acid is indicated by 'd' in the figure?
(a) Glycine
(b) Methionine
(c) Alanine
(d) Valine

Mishal Gul

Numerade Educator

Problem 66

'Beads-on-string' structure can be viewed under
(a) Light microscope
(b) Compound microscope
(c) Confocal laser microscope
(d) Electron microscope

Mishal Gul

Numerade Educator

00:46

Problem 67

'Beads-on-string' structure in chromatin is packaged to form
(a) Nucleosomes
(b) Solenoids
(c) Chromatin fibres
(d) Chromatids

Mishal Gul

Numerade Educator

Problem 68

Chromatin fibres coil and condense at stage of cell division to form
(a) Prophase, nucleosomal
(b) Telophase, solenoid
(c) Metaphase, chromosome
(d) Anaphase, chromatid

Mishal Gul

Numerade Educator

01:11

Problem 69

Apart from histones, chromatin at higher level of coiling requires which proteins?
(a) Nco histonc complex protcins
(b) Nonc-histone chromatic proteins
(c) Non-histone chromosomal proteins
(d) Nonc of these

Mishal Gul

Numerade Educator

Problem 70

Which protein is indicated by 'a' in the figure?
(a) Threonine
(b) Serine
(c) Tyrosine
(d) Methionine

Mishal Gul

Numerade Educator

Problem 71

Which protein is indicated by 'b' in the figure?
(a) Threonine
(b) Serine
(c) Tyrosine
(d) Methionine

Mishal Gul

Numerade Educator

Problem 72

In the nucleus, the region of chromatin which is loosely packed is known as
(a) Heterochromatin
(b) Chromatin fibres
(c) Euchromatin
(d) Chromosome

Mishal Gul

Numerade Educator

Problem 73

Which is true about the structure of heterochromatin?
(a) Loosely packed; Stain light
(b) Loosely packed; Stain dark
(c) Densely packed; Stain light
(d) Densely packed; Stain dark

Mishal Gul

Numerade Educator

Problem 74

Transformation experiments in search of genetic material were performed by
(a) G. J. Mendel
(b) T. H. Morgan
(c) F. Griffith
(d) F. H. Crick

Mishal Gul

Numerade Educator

Problem 75

Griffith carried out his experiments on mice using which pathogenic bacterium?
(a) Haemophilus influenzae
(b) Corynebacterium diphtheria
(c) Streptococcus pneumoniae
(d) Yersinia pestis

Mishal Gul

Numerade Educator

Problem 76

In Griffith's experiment, heat killed S-strain when injected into mice resulted in
(a) Diseased condition only
(b) Death only
(c) No disease or death
(d) Hybrid formation

Mishal Gul

Numerade Educator

View

Problem 77

The transforming principle in Griffith's experiment was detected
(a) When live S-strain of S. pneumoniae were injected in R-stain.
(b) When live R-strain of S. pneumoniae were injected in S-strain.
(c) When heat killed R-strain of S. pneumoniae were injected in S-strain.
(d) When heat killed S-strain of $S$. pneumonia were injected in R-strain.

Mishal Gul

Numerade Educator

00:44

Problem 78

Oswald Avery, Colin MacLeod and Maclyn McCarty $(1933-44)$ worked to determine the nature of 'transforming principle' in Griffith's cxperiment.
(a) Physical
(b) Morphological
(c) Structural
(d) Biochemical

Mishal Gul

Numerade Educator

Problem 79

What is indicated by 'd' in the figure?
(a) Continuous synthesis
(b) Newly synthesized strands
(c) Template DNA
(d) Discontinuous synthesis

Mishal Gul

Numerade Educator

00:17

Problem 80

What does ' $b$ ' represent in figure?
(a) Template DNA
(b) Continuous synthesis
(c) Discontinuous synthesis
(d) Newly synthesized strands

Mishal Gul

Numerade Educator

Problem 81

What is indicated by 'a' in the figure?
(a) Newly synthesized strands
(b) Discontinuous synthesis
(c) Template DNA
(d) Continuous synthesis

Mishal Gul

Numerade Educator

Problem 82

What does 'c' represent in the figure?
(a) Template DNA
(b) Continuous synthesis
(c) Discontinuous synthesis
(d) Newly synthesized strands

Mishal Gul

Numerade Educator

00:10

Problem 83

RNA digesting enzymes are commonly known as
(a) Ribozymes
(b) Ribosomes
(c) RNases
(d) Ribulose

Mishal Gul

Numerade Educator

01:26

Problem 84

What is the difference between DNAs and DNase?
(a) Genetic material-DNA digesting enzyme
(b) DNA digesting enzyme Genetic material
(c) Protein-Peptide
(d) None of these

Mishal Gul

Numerade Educator

Problem 85

The experiment which provides unequivocal proof that DNA is genetic material and it came from the experiment of
(a) Watson and Crick
(b) Wilkins and Franklin
(c) Hershey and Chase
(d) Avery, MacLeod and Maclyn McCarty

Mishal Gul

Numerade Educator

00:54

Problem 86

In the Hershey-Chase experiments the following isotopes were used
(a) ${ }^{32} \mathrm{~S},{ }^{30} \mathrm{P}$
(b) ${ }^{31} \mathrm{~S},{ }^{29} \mathrm{P}$
(c) ${ }^{35} \mathrm{~S},{ }^{32} \mathrm{P}$
(d) ${ }^{34} \mathrm{~S},{ }^{33} \mathrm{p}$

Mishal Gul

Numerade Educator

01:18

Problem 87

The Hershey-Chase experiments show which of the following steps chronologically?
(a) Blending, Infection, Centrifugation
(b) Centrifugation, Infection, Blending
(c) Infection, Centrifugation, Blending
(d) Infection, Blending, Centrifugation

Mishal Gul

Numerade Educator

01:00

Problem 88

In Hershey-Chase experiments, ${ }^{35} \mathrm{~S}$ labelled and ${ }^{32} \mathrm{P}$ labelled $\quad$ respectively.
(a) Bacteria, DNA
(b) DNA, Protein
(c) Protein, DNA
(d) DNA, mRNA

Mishal Gul

Numerade Educator

Problem 89

DNA is a preferred genetic material over RNA due to one of the following reasons
(a) Bases are arranged linearly in a single strand.
(b) Bases show less propensity of mutation.
(c) $2^{\prime} \mathrm{OH}$ group in RNA is more liable.
(d) None of the above

Mishal Gul

Numerade Educator

Problem 90

Which was the first genetic material?
(a) DNA
(b) RNA
(c) Proteins
(d) None of these

Mishal Gul

Numerade Educator

01:01

Problem 91

'It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.' This was a statement of
(a) Wilkins and Franklin
(b) Hershey and Chase
(c) Avery, McLeod, McCarty
(d) Watson and Crick

Mishal Gul

Numerade Educator

Problem 92

Which cxperiment is shown in the figurc?
(a) Griffith's experiment
(b) Avery, MacLeod and McCarty
(c) Hershey-Chase experiment
(d) Meselson and Stahl experiment

Mishal Gul

Numerade Educator

Problem 93

What is indicated by 'a' in the figure?
(a) Bacteriophage
(b) Bacterium
(c) Lichen
(d) Fungus

Mishal Gul

Numerade Educator

00:22

Problem 94

What is indicated by 'b' in the figure?
(a) ${ }^{35} \mathrm{~S}$
(b) ${ }^{32} \mathrm{~S}$
(c) ${ }^{30} \mathrm{P}$
(d) ${ }^{32} \mathrm{P}$

Mishal Gul

Numerade Educator

Problem 95

What is indicated by 'c' in the figure?
(a) ${ }^{35} \mathrm{~S}$
(b) ${ }^{32} \mathrm{~S}$
(c) ${ }^{30} \mathrm{P}$
(d) ${ }^{32} \mathrm{P}$

Mishal Gul

Numerade Educator

Problem 96

After replication, each DNA molecule has one parental and one newly synthesized strand. This scheme is referred to as
(a) Fully conservative
(b) Mutation
(c) Crossing over
(d) Semiconservative

Mishal Gul

Numerade Educator

Problem 97

Semiconservative replication of DNA was demonstrated by
(a) Meselson and Stahl
(b) Watson and Crick
(c) Hershey and Chase
(d) Wilkins and Franklin

Mishal Gul

Numerade Educator

Problem 98

In Meselson and Stahl experiment, E. coli was grown in a medium containing
(a) ${ }^{40} \mathrm{KCl}$
(b) ${ }^{24} \mathrm{NaCl}$
(c) ${ }^{15} \mathrm{NH}_{4} \mathrm{Cl}$
(d) $\mathrm{CsCl}$

Mishal Gul

Numerade Educator

Problem 99

In Meselson and Stahl experiment, ${ }^{15} \mathrm{~N}$ can only be differentiated on the basis of
(a) Radioactivity
(b) Radioactive t $1 / 2$
(c) Physical observation
(d) Density gradient

Mishal Gul

Numerade Educator

Problem 100

Taylor and his colleagues used which plant to detect the distribution of newly synthesized DNA?
(a) Pisum sativum
(b) Mirabilis jalapa
(c) Vicia faba
(d) Triticum aestivum

Mishal Gul

Numerade Educator

Problem 101

Taylor and his colleagues used which radioactive probe to detect the distribution of newly synthesized DNA in chromosomes?
(a) Thymine
(b) Ademine
(c) Guanine
(d) Cytosine

Mishal Gul

Numerade Educator

01:25

Problem 102

The process of replication of DNA in E. coli requires an enzyme referred to as
(a) RNA dependent DNA polymerase
(b) RNA polymerase
(c) DNA dependent DNA polymerase
(d) DNA ligase

Mishal Gul

Numerade Educator

Problem 103

E. coli completes replication in approximately
(a) 15 minutes
(b) 20 minutes
(c) 18 minutes
(d) 40 minutes

Mishal Gul

Numerade Educator

01:01

Problem 104

Dcoxyribonucleotide triphosphate serves the dual purpose of and in the process of replication of DNA.
(a) Enzyme, substratc
(b) Catalyst, substrate
(c) Substrate, cnergy provider
(d) Energy, mutage provider

Mishal Gul

Numerade Educator

00:47

Problem 105

The average rate of polymerization of deoxyribonucleotides in E. coli DNA replication process is
(a) $2500 \mathrm{bp} / \mathrm{s}$
(b) $2000 \mathrm{bp} / \mathrm{s}$
(c) $3000 \mathrm{bp} / \mathrm{s}$
(d) $3500 \mathrm{bp} / \mathrm{s}$

Mishal Gul

Numerade Educator

Problem 106

DNA dependent DNA polymerase catalyses polymerization in direction only (in terms of newly synthesized strands).
(a) $5 \rightarrow 3$
(b) $3^{\prime} \rightarrow 5^{\prime}$
(c) $5^{\prime} \rightarrow 3^{\prime}$
(d) $3 \rightarrow 5$

Mishal Gul

Numerade Educator

Problem 107

The figure shows an essential biomolecule associated with which cell organelle?
(a) Endoplasmic reticulum
(b) Ribosome
(c) Nucleus
(d) Golgi complex

Mishal Gul

Numerade Educator

Problem 108

What is indicated by 'a' in the figure?
(a) RNA
(b) DNA
(c) Histone octamer
(d) H1 histone

Mishal Gul

Numerade Educator

Problem 109

What is indicated by 'b' in the figure?
(a) RNA
(b) DNA
(c) Histone octamer
(d) Hl histone

Mishal Gul

Numerade Educator

Problem 110

What is indicated by 'd' in the figure?
(a) Core of histone molecule
(b) Part of histone molecule
(c) Histone octamer
(d) DNA

Mishal Gul

Numerade Educator

00:38

Problem 111

What is indicated by 'c' in the figure?
(a) Core of histone molecule
(b) Part of histone molecule
(c) Histone octamer
(d) DNA

Mishal Gul

Numerade Educator

Problem 112

The whole structure indicated in the figure is of
(a) Chromosome
(b) Nucleolus
(c) Nucleosome
(d) Proteasome

Mishal Gul

Numerade Educator

00:55

Problem 113

Discontinuously synthesized strands of DNA adjacent to DNA template are joined together by
(a) $5 \rightarrow 3$, DNA endonucleace
(b) $3^{\prime} \rightarrow 5^{\prime}$, DNAase
(c) $5^{\prime} \rightarrow 3^{\prime}$, DNA ligase
(d) $5 \rightarrow 3$, DNA ligase

Mishal Gul

Numerade Educator

Problem 114

During which phase of the cell cycle does replication of DNA takes place in eukaryotes?
(a) $\mathrm{G}_{1}$
(b) $\mathrm{G}_{0}$
(c) $\mathrm{S}$
(d) $\mathrm{G}_{2}$

Mishal Gul

Numerade Educator

Problem 115

The process of copying genetic information from DNA to RNA is known as
(a) Translation
(b) Transduction
(c) Transcription
(d) Transformation

Mishal Gul

Numerade Educator

Problem 116

The product of transcription process is in fact
(a) Entire segment of DNA copied to RNA
(b) Only segment of DNA copied to RNA
(c) Both (a) and (b)
(d) None of these

Mishal Gul

Numerade Educator

01:04

Problem 117

In the process of transcription, the strand of DNA with polarity acts as a strand.
(a) $5^{\prime} \rightarrow 5^{\prime}$, Coding strand
(b) $3^{\prime} \rightarrow 5^{\prime}$ Template strand
(c) $3^{\prime} \rightarrow 3^{\prime}$, Coding strand
(d) $5^{\prime} \rightarrow 3^{\prime}$, Template strand

Mishal Gul

Numerade Educator

Problem 118

The promoter and flank the structural gene in a transcription unit.
(a) Structure
(b) Regulator
(c) Operator
(d) Terminator

Mishal Gul

Numerade Educator

Problem 119

A segment of DNA coding for a polypeptide is termed as
(a) Intron
(b) Exon
(c) Cistron
(d) Distron

Mishal Gul

Numerade Educator

00:48

Problem 120

Which cxpcriment is shown in the figurc?
(a) Griffith's experiment
(b) Hershay and Chase experiment
(c) Meselson and Stahl experiment
(d) Wastson and Crick experiment

Mishal Gul

Numerade Educator

Problem 121

What is indicated by 'a' in the figure?
(a) Centrifugal force
(b) Centripetal force
(c) Gravitational force
(d) Radioactive force

Mishal Gul

Numerade Educator

Problem 122

What is indicated by 'b' in the figure?
(a) Heavy
(b) Hybrid
(c) Light
(d) Heavy hybrid

Mishal Gul

Numerade Educator

Problem 123

What is indicated by 'c' in the figure?
(a) Heavy
(b) Hybrid
(c) Light
(d) Heavy hybrid

Mishal Gul

Numerade Educator

Problem 124

What is indicated by 'd' in the figure?
(a) Hybrid
(b) Light and hybrid
(c) Heavy and hybrid
(d) Heavy and light

Mishal Gul

Numerade Educator

00:38

Problem 125

The coding sequences of DNA are known as and the intervening sequences are known as $\quad$ respectively.
(a) Exon, intron
(b) Intron, exon

Mishal Gul

Numerade Educator

Problem 126

In bacteria, which of the following plays a structural and catalytic role in the translation process?
(a) $\mathrm{mRNA}$
(b) rRNA
(c) tRNA
(d) DNA

Mishal Gul

Numerade Educator

01:04

Problem 127

What are the components required for the initiation of transcription in bacteria?
(a) RNA polymerase only
(b) Promoter, RNA polymerase and $\rho$ -factor
(c) $\rho$ factor only
(d) $\sigma$ factor only

Mishal Gul

Numerade Educator

Problem 128

$\rho$ -factor in the process of transcription in bacteria is also known as
(a) Initiation factor
(b) Elongation factor
(c) Termination factor
(d) Vital factor

Mishal Gul

Numerade Educator

03:42

Problem 129

In bacteria, in context of $\mathrm{mRNA}$, which of the following is not true?
(a) Transcription and translation takes place in different compartment.
(b) Post-transcriptional modifications are required like splicing.
(c) Translation occurs only after transcription.
(d) All the above

Nagamalla Rama Krishna

Numerade Educator

02:59

Problem 130

The total number of RNA polymerase found in eukaryotes is
(a) 3
(b) 4
(c) 2
(d) 5

Nagamalla Rama Krishna

Numerade Educator

01:20

Problem 131

Which of the following RNA is transcribed by RNA polymerase II in eukaryotes?
(a) tRNA
(b) rRNA
(c) snRNA
(d) hnRNA

Nagamalla Rama Krishna

Numerade Educator

01:12

Problem 132

RNA polymerase I transcribes in eukaryotes.
(a) tRNA
(b) rRNA
(c) snRNA
(d) hnRNA

Nagamalla Rama Krishna

Numerade Educator

01:47

Problem 133

In cukaryotes, RNA polymerase III is responsible for synthesis of
(a) $28 \mathrm{~S}$ RNA, $18 \mathrm{~S}$ RNA and $5.8 \mathrm{~S}$ RNA
(b) tRNA, hnRNA, rRNA
(c) tRNA, 5sRNA, snRNA
(d) hnRNA, tRNA, rRNA

Sirisa Reddy

Numerade Educator

01:59

Problem 134

The intervening sequences in the primary transcript of mRNA are removed by
(a) Recombination
(b) Linkage
(c) Capping
(d) Splicing

Nagamalla Rama Krishna

Numerade Educator

02:39

Problem 135

Additional post-transcriptional processing like capping and tailing is characteristic to
(a) rRNA
(b) hnRNA
(c) snRNA
(d) tRNA

Sirisa Reddy

Numerade Educator

02:54

Problem 136

Which classical model proposed by Watson and Crick is represented by this figurc?
(a) Fully conservative DNA transcription
(b) Semi-conservative RNA replication
(c) Semi-conservative DNA replication
(d) Non-conservative DNA replication

Dr. Anas Syed

Numerade Educator

02:00

Problem 137

In a post-transcriptional modification, capping adds an unusual nucleotide like
(a) Guanosine triphosphate
(b) Methyl gunanine triphosphate
(c) Methyl guanosine triphosphate
(d) Adenosine triphosphate

Nagamalla Rama Krishna

Numerade Educator

03:00

Problem 138

In a post-transcriptional modification called tailing, residues are added at the of mRNA.
(a) Adenylate, $5^{\prime}$ - end
(b) Guanylate, $3^{\prime}$ - end
(c) Adenvlate, $3^{\prime}$ - end
(d) Guanvlate. 5'- end

Nagamalla Rama Krishna

Numerade Educator

Problem 139

mRNA is in fact
(a) Unprocessed rRNA
(b) Unprocessed hnRNA
(c) Processed hnRNA
(d) Processed mRNA itself

Mishal Gul

Numerade Educator

Problem 140

A physicist, George Gamow, argued that genetic code is a combination of nucleotides.
(a) 3
(b) 2
(c) 4
(d) 1

Nidhi Singhi

Numerade Educator

Problem 141

Humans requires codons to synthesize 20 amino acids.
(a) 64 codons
(b) 61 codons
(c) 62 codons
(d) 60 codons

Nidhi Singhi

Numerade Educator

00:35

Problem 142

The chemical method developed by was instrumental in synthesizing RNA molccules with defined combination of bases.
(a) Marshall Nirenberg
(b) George Gamow
(c) Har Gobind Khorana
(d) F. H. C. Crick

Sana Riaz

Numerade Educator

00:35

Problem 143

cell-free system for protein synthesis finally helped the genetic code to be deciphered.
(a) Gcorge Gamow's
(b) Marshall Nirenberg's
(c) Har Gobind Khorana's
(d) J. D. Watson's

Nidhi Singhi

Numerade Educator

02:24

Problem 144

Some amino acids are coded by more than one codon. Hence the genetic code exhibits
(a) Specificity
(b) Selectivity
(c) Degeneracy
(d) Regenerancy

Sana Riaz

Numerade Educator

Problem 145

The codon AUG has dual function as it codes for and also acts as a codon.
(a) Phenylalanine, initiator
(b) Methionine, terminator
(c) Methionine, regulator
(d) Methionine, initiator

Nidhi Singhi

Numerade Educator

Problem 146

Sickle cell anaemia is a classic example of
(a) Frame shift mutation
(b) Point mutation
(c) Deletion mutation
(d) Duplication mutation

Mishal Gul

Numerade Educator

00:52

Problem 147

In sickle cell anaemia, which amino acid modification occurs in the $\beta$ -chain of amino acid?
(a) Valine $\rightarrow$ Glutamate
(b) Threonine $\rightarrow$ Valine
(c) Tyrosine $\rightarrow$ Glutamate
(d) Glutamate $\rightarrow$ Valine

Mishal Gul

Numerade Educator

Problem 148

tRNA was earlier called
(a) Adapter molecule
(b) Special RNA
(c) Protein carrying RNA
(d) Soluble RNA

Nidhi Singhi

Numerade Educator

00:16

Problem 149

For the initiation of translation process, specific tRNAs involved are known as
(a) Helper tRNA
(b) Assistor tRNA
(c) Initiator tRNA
(d) Terminal tRNA

Nidhi Singhi

Numerade Educator

View

Problem 150

The picture is taken using microscope.
(a) Phase contrast
(b) Electron
(c) Bright field
(d) Fluorescence

Sirisa Reddy

Numerade Educator

Problem 151

The picture shows characteristic coiling of DNA known as
(a) Strings-on-beads
(b) beads-on-strings
(c) Nanobead coiling
(d) None of these

Sana Riaz

Numerade Educator

Problem 152

The process of polymerization of amino acids to polypeptide is known as
(a) Pepto-polymerization
(b) Transcription
(c) Translation
(d) Transformation

Nidhi Singhi

Numerade Educator

01:30

Problem 153

Charging of tRNA is also known as
(a) Acylation
(b) Transamination
(c) Amine Alkylation
(d) Aminoacylation

Sana Riaz

Numerade Educator

00:52

Problem 154

tRNA for serine bears anticodon
(a) $\mathrm{AUG}$
(b) UAC
(c) UCA
(d) UGA

Nidhi Singhi

Numerade Educator

Problem 155

The structure of tRNA resembles which leaf?
(a) Olive
(b) Neem
(c) Clove
(d) Clover

Nidhi Singhi

Numerade Educator

Problem 156

Ribosomes are the cellular factory for synthesis of
(a) Carbohydrates
(b) Enzymes
(c) Proteins
(d) Lipids

Nidhi Singhi

Numerade Educator

Problem 157

Ribozyme in bacteria is $\quad$ rRNA.
(a) $30 \mathrm{~S}$
(b) $32 \mathrm{~S}$
(c) $23 \mathrm{~S}$
(d) $21 \mathrm{~S}$

Nidhi Singhi

Numerade Educator

Problem 158

Additional sequences on mRNA referred to as are not translated.
(a) Variable number tandem repeats
(b) Non coding sequence
(c) Untranscribed regions
(d) Untranslated regions

Nidhi Singhi

Numerade Educator

01:22

Problem 159

In Eukaryotes, which of the following mechanisms is not correct in terms of regulation of gene expression?
(a) Transcription
(b) Splicing
(c) Transport of mRNA from cytoplasm to nucleus
(d) Translation

Mishal Gul

Numerade Educator

Problem 160

$\beta$ -galactosidase is synthesized by $\mathrm{E}$. coli to catalyze hydrolysis of into and glucose.
(a) Galactose, lactose
(b) Galactose, glucose
(c) Lactose, galactose
(d) Maltose, galactose

Nidhi Singhi

Numerade Educator

01:09

Problem 161

Lac operon was elucidated by
(a) Watson, Crick
(b) Jacob, Monod
(c) Johansson
(d) Miescher

Sana Riaz

Numerade Educator

Problem 162

A polycistronic structural gene is regulated by a common promoter and regulator gene in bacteria and is commonly termed as
(a) Codon
(b) Operon
(c) Genetic code
(d) None of these

Nidhi Singhi

Numerade Educator

00:40

Problem 163

Regulatory gene 'I' in lac operon is
(a) Inducer
(b) Inhibitor
(c) Structure
(d) Initiator

Nidhi Singhi

Numerade Educator

00:32

Problem 164

What is indicated by ' $\mathrm{d}$ ' in the figure?
(a) RNA polymerase
(b) DNA helix
(c) Sigma factor
(d) Promoter

Mishal Gul

Numerade Educator

Problem 165

What is indicated by 'b' in the figure?
(a) Sigma factor
(b) RNA
(c) DNA helix
(d) Promoter

Mishal Gul

Numerade Educator

Problem 166

What does 'h' represent in the figure?
(a) RNA polymerase
(b) RNA
(c) Promoter
(d) Rho factor

Mishal Gul

Numerade Educator

Problem 167

Out of the 3 structural genes $\mathrm{z}, \mathrm{y}$ and a, the gene (s) which gene of E. coli lac Operon code for permease?
(a) $\mathrm{z}$
(b) $\mathrm{s}$
(c) $\mathrm{y}$
(d) Both (b) and (c)

Mishal Gul

Numerade Educator

Problem 168

Repressor protein in lac operon concept binds to which gene?
(a) $\mathrm{d}$
(b) $i$
(c) $\underline{\circ}$
(d) $\mathrm{z}$

Nidhi Singhi

Numerade Educator

00:46

Problem 169

In lac operon, the inducer binds to to initiate the synthesis of enzymes responsible for lactose metabolism.
(a) i gene
(b) Repressor
(c) O gene
(d) $Z$ gene

Nidhi Singhi

Numerade Educator

Problem 170

Lac operon operates in E. Coli
(a) Occasionally
(b) Frequently
(c) All time
(d) Sometimes

Nidhi Singhi

Numerade Educator

Problem 171

Generally the regulation of lac operon by repressor is referred to as regulation.
(a) Positive
(b) Negative
(c) Feedback
(d) Both (b) and (c)

Nidhi Singhi

Numerade Educator

Problem 172

Considering the cost of sequencing 1 bp to be US $3 \$, 4$ the approximate cost of HGP (Human Genome Project) would come out to be
(a) 3 billion
(b) 9 million
(c) 9 billion
(d) 3 million

Mishal Gul

Numerade Educator

Problem 173

What is indicated by 'a' in the figure?
(a) Maternal chromosome
(b) Paternal chromosome
(c) Foetal chromosome
(d) Sister chromosome

Mishal Gul

Numerade Educator

Problem 174

What is indicated by 'b' in the figure?
(a) Maternal chromosome
(b) Paternal chromosome
(c) Foetal chromosome
(d) Sister chromosome

Mishal Gul

Numerade Educator

Problem 175

HGP was closely associated with the rapid development of
(a) Chemo informatics
(b) Modern genetics
(c) Pharmaco informatics
(d) Bioinformatics

Mishal Gul

Numerade Educator

01:18

Problem 176

Human Genome project was a $\mathbf{X}$ year long project starting from $\mathbf{Y}$ to $\mathbf{Z}$.
(a) $X=13, Y=1980, X=1993$
(b) $\mathrm{X}=12, \mathrm{Y}=1990, \mathrm{Z}=2002$
(c) $\mathrm{X}=13, \mathrm{Y}=1990, \mathrm{Z}=2003$
(d) $\mathrm{X}=14, \mathrm{Y}=1990, \mathrm{Z}=2004$

Mishal Gul

Numerade Educator

Problem 177

ELSI strands for
(a) Ethical, Logical and Society Issues
(b) Ethical, Legal and Society Issues
(c) Ethical, Logical and Social Issues
(d) Ethical, Legal and Social Issues

Mishal Gul

Numerade Educator

Problem 178

Caenorhabditis elegans is a free-living non-pathogenic
(a) Annelid
(b) Nematode
(c) Crustocean
(d) Mammal

Mishal Gul

Numerade Educator

Problem 179

Expressed sequence tags (ESTs) is an approach practised in
(a) DNA fingerprinting
(b) DNA sequencing
(c) DNA replicating
(d) DNA transformation

Mishal Gul

Numerade Educator

Problem 180

Sequencing the whole genome of an organism into coding and non-coding sequences is termed as
(a) Sequence determination
(b) Sequence detection
(c) Sequence annotation
(d) Sequence completion

Mishal Gul

Numerade Educator

Problem 181

BAC, a vector used in biotechnology for cloning, stands for
(a) Bacterial Actual Chromosome
(b) Bacterial Artificial Chromosome
(c) Bacterial Annoted Chromosome
(d) Nonc of thesc

Mishal Gul

Numerade Educator

Problem 182

The credit for developing a method for determination of DNA as well as protcin scquence goes to
(a) Sanger
(b) Watson
(c) Taylor
(d) Monod

Mishal Gul

Numerade Educator

Problem 183

In HGP, the chromosome was completed in May 2006 .
(a) 2
(b) 1
(c) 3
(d) 4

Mishal Gul

Numerade Educator

00:48

Problem 184

Which of the following is NOT a salient feature of the Human Genome Project?
(a) The human genome contains $3614.7$ million nucleotide bases.
(b) Less than 2 per cent genome codes for proteins.
(c) Over 50 per cent of the genes discovered are yet to be investigated regarding their functions.
(d) Chromosome Y has the fewest of genes.

Mishal Gul

Numerade Educator

Problem 185

Under HGP, the scientists have located $1.4$ million locations where difference in single DNA base exists. It is termed as
(a) Microsatellites
(b) Single nucleotide polymorphism

Mishal Gul

Numerade Educator

Problem 186

DNA fingerprinting is based on the principle of identifying sequences of DNA.
(a) Satellite
(b) Variable
(c) Mutated
(d) Repetitive

Mishal Gul

Numerade Educator

Problem 187

Variations at genetic level in nucletodies is termed as
(a) Allotropy
(b) Polymorphism
(c) Isomerism
(d) Tautomerism

Mishal Gul

Numerade Educator

Problem 188

If inheritable mutation is observed in a population at high frequency, it is termed as
(a) DNA mutation
(b) DNA isomerism
(c) DNA polymorphism
(d) None of these

Mishal Gul

Numerade Educator

Problem 189

The technique of was discovered by Alec Jeffreys.
(a) DNA culture
(b) DNA modification
(c) DNA mutation
(d) DNA fingerprinting

Mishal Gul

Numerade Educator

Problem 190

A well-known technique to amplify a small portion of DNA is termed as
(a) PCR
(b) VNTR
(c) UTR
(d) EST

Mishal Gul

Numerade Educator

Problem 191

VNTRs vary in size from to
(a) $0.1$ to 20 bases
(b) $0.1$ to 20 kilobases
(c) $0.1$ to 20 hectobases
(d) $0.1$ to 20 decabases

Mishal Gul

Numerade Educator

00:22

Problem 192

Similar DNA finger printing is obtained for
(a) Dizygotic twins
(b) Monozygotic twins
(c) Polyzygotic twins
(d) None of these

Mishal Gul

Numerade Educator

00:17

Problem 193

In DNA fingerprinting, the hybridized strands are detected by
(a) Radiometery
(b) Radioscopy
(c) Autoradiography
(d) Scintillation counter

Mishal Gul

Numerade Educator

00:50

Problem 194

Under HGP, the largest known human gene was of
(a) Somatotropin
(b) Dystrophin
(c) Insulin
(d) Somatostatin

Nagamalla Rama Krishna

Numerade Educator

Problem 195

What is indicated by 'a' in figure?
(a) H-bond
(b) Ionic bond
(c) Covalent bond
(d) Van der Waals bond

Mishal Gul

Numerade Educator

01:05

Problem 196

Assertion: DNA act as the genetic material in most of the organisms. Reason: DNA is chemically and structurally a stable molecule; it has the power of replication.

Mishal Gul

Numerade Educator

Problem 197

Assertion: In RNA, the uracil is found at the place of thymine. Reason: $5-$ methyl uracil is the chemical name for thymine.

Mishal Gul

Numerade Educator

Problem 198

Assertion: There is uniform distance between two strands of DNA. Reason: Purine always comes opposite to pyrimidine.

Mishal Gul

Numerade Educator

Problem 199

Assertion: Chargaff rule is applicable to RNA. Reason: RNA is a double standard molecule.

Mishal Gul

Numerade Educator

Problem 200

Assertion: Viruses having shorter life span, mutate and evolve faster. Reason: Viruses have generally RNA genome.

Mishal Gul

Numerade Educator

Problem 201

Assertion: RNA was the first genetic material. Reason: Essential life processes (such as metabolism, translation, splicing, etc.) evolve around RNA.

Mishal Gul

Numerade Educator

Problem 202

Assertion: UTRs are present at both 5 ' end and 3'end in mRNA. Reason: UTRs are required for efficient translation process.

Mishal Gul

Numerade Educator

Problem 203

Assertion: DNA polymerase-I acts as proofreader. Reason: DNA polymerase-I removes mismatched nucleotides.

Mishal Gul

Numerade Educator

00:32

Problem 204

Assertion: The genetic codes are commaless. Reason: Genetic codes are overlapping.

Mishal Gul

Numerade Educator

Problem 205

Assertion: Cytoplasmic inheritance occurs only due to plasmagenes. Reason: Plasmagenes are restricted to only nucleus.

Mishal Gul

Numerade Educator

Problem 206

Assertion: Enzymes required for DNA replication are efficient enzymes Reason: They can polymerise large number of nucleotides in very short time.

Mishal Gul

Numerade Educator

Problem 207

Assertion: DNA replication occurs within a small opening of the DNA helix. Reason: DNA can not be separated in its entire length due to very high energy requirement.

Mishal Gul

Numerade Educator

Problem 208

Assertion: A piece of DNA if propagated through recombinant DNA procedures requires a vector. Reason: Vector provides origin of replication.

Mishal Gul

Numerade Educator

Problem 209

Assertion: A failure in cell division results into polyploidy. Reason: Polyploidy is a chromosomal anomaly.

Mishal Gul

Numerade Educator

Problem 210

Assertion: Both the strands of DNA are not copied during process of transcription. Reason: The two molecules of RNA complementary to each other form the double stranded RNA and this would prevent RNA from being translated into protein.

Mishal Gul

Numerade Educator