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Assertion: ADA deficiency can be cured by bone marrow transplantation. Reason: ADA deficiency can be treated by enzyme replacement therapy.
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ADA (Adenosine Deaminase) deficiency is a rare genetic disorder that damages the immune system and causes severe combined immunodeficiency (SCID). Show more…
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Permanent cure for ADA deficiency is (a) Genetically engineered lymphocyte (b) Bone marrow transplantation (c) Enzyme replacement therapy (d) ADA gene introduced in early embryonic stages
Because it is a "transplant" that can include APCs and T cells from the donor, a bone marrow transplant may induce a very specific type of rejection known as _____ disease.
Assertion: A functional ADA $c$ DNA is introduced in lymphocyte using retroviral vector. Reason: Disarmed retrovirus is use to deliver gene in animal cells.
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