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Assertion: Myasthenia gravis is autoimmune disorder. Reason: It results due to antibodies are formed that block our own nicotinic acetylcholine receptor at neuromuscular junction.
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It is an autoimmune disorder. This is stated in the assertion and is correct. So, the assertion is true. In LaTeX format: \textbf{ Show more…
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What is the mechanism of muscle weakness in Myasthenia gravis? Presence of antibodies against the auto receptors which involve in the uptake of excessive Ach. The disease is autosomal recessive which decreases expression of acetylcholinesterase (AChE), an enzyme that breaks down. Presence of antibodies against Na+ channels involved in the entrance of Choline into the presynaptic cells, therefore blocking the Ach synthesis. Presence of antibodies against cholinergic receptors at the neuromuscular junction.
Myasthenia gravis is an autoimmune disease that initially presents with muscle weakness and can progress to complete impairment of muscle movement. The diagram compares a healthy individual with an individual suffering from this disease. Which statement best explains what happens to bring about this disease? a. The body produces antibodies against nerve cells, which prevents the nerve cells from releasing acetylcholine during signal transmissions to muscle. b. The body produces antibodies against acetylcholine, which prevents acetylcholine from transmitting signals from nerves to muscle. c. The body produces antibodies against receptors in muscle, which prevents acetylcholine from binding and completing nerve signal transmission. d. The body produces antibodies against acetylcholine, which prevents acetylcholine from breaking down after signal transmission is complete.
In the condition myasthenia gravis, antibodies bind to and block certain receptors on muscle cells, preventing muscle contraction. This condition is best classified as an a. immunodeficiency disorder. b. exaggerated immune reaction. c. allergic reaction. d. autoimmune disorder.
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