00:01
For this question, we are trying to understand the function of our different complement proteins.
00:07
So these are a series of about nine different proteins, which we label c1 through c9, that are going to respond to an immunoglobulin binding or to an antibody antigen complex.
00:28
So in this circumstance, your c1 protein is going to, say, bind to this antibody antigen complex.
00:36
And cause a complement cascade, as you call it, in order to get a final response that causes cell lysis, typically of a pathogen cell.
00:51
This consists of creating several intermediary proteins, such as c4b2a3b, which is going to activate a larger complex called the mac complex, which is c7c8.
01:13
And c9.
01:19
And in the creation of this first large product of c4b, 2a, 3b, you're going to get other precursors that come along, such as c4a, you're going to get 2b, and 3a.
01:35
And these will hold certain functions of anaphylotoxins or opsonins, which are basically going to improve the inflammation response.
01:53
And the immune response...