Question
If codons were six bases long, what kind of product would you expect from a repeating tetranucleotide such as poly (UUCG)?
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Codons are sequences of three nucleotides that correspond to specific amino acids in protein synthesis. If codons were six bases long, each codon would consist of two sets of three nucleotides. Show more…
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Which polypeptide sequences would you expect to result from a synthetic mRNA with the repeating sequence 5'-UUUGGGUUUGGGUUUGGG-3'?
Suppose you were to construct a synthetic RNA from a repeating dinucleotide (e.g., $A G A G A G A G)$ and then use this RNA as a messenger to synthesize a polypeptide in an in vitro protein-synthesizing system, such as that used by Nirenberg and Matthaei to produce polyphenylalanine. What type of polypeptide would you make from this particular polynucleotide? Would you expect to have more than one type of polypeptide produced? Why or why not?
Suppose you were to construct a synthetic RNA from a repeating dinucleotide (e.g., AGAGAGAG) and then use this RNA as a messenger to synthesize a polypeptide in an in vitro protein-synthesizing system, such as that used by Nirenberg and Matthaei to produce polyphenylalanine. What type of polypeptide would you make from this particular polynucleotide? Would you expect to have more than one type of polypeptide produced? Why or why not?
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