Question

The blob operon produces enzymes that convert compound A into compound B. The operon is controlled by a regulatory gene $S$. Normally, the enzymes are synthesized only in the absence of compound B. If gene $S$ is mutated, the enzymes are synthesized in the presence and in the absence of compound B. Does gene $S$ produce a repressor or an activator? Is this operon inducible or repressible?

Name: Problem 13, Chapter 16: Genetics: A Conceptual Approach
Uploaded: 2020-06-30T00:01:23-08:00
Duration: 2 min 22 s
Channel: Dennis Howard
Description: The blob operon produces enzymes that convert compound A into compound B. The operon is controlled by a regulatory gene S. Normally, the enzymes are synthesized only in the absence of compound B. If gene S is mutated, the enzymes are synthesized in the presence and in the absence of compound B. Does gene S produce a repressor or an activator? Is this operon inducible or repressible?

   The blob operon produces enzymes that convert compound A into compound B. The operon is controlled by a regulatory gene $S$. Normally, the enzymes are synthesized only in the absence of compound B. If gene $S$ is mutated, the enzymes are synthesized in the presence and in the absence of compound B. Does gene $S$ produce a repressor or an activator? Is this operon inducible or repressible?

Genetics: A Conceptual Approach

Benjamin Pierce 5th Edition

Chapter 16, Problem 13

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Solved by Expert Dennis Howard

06/30/2020

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The blob operon produces enzymes that convert compound A into compound B. The operon is controlled by a regulatory gene $S$. Normally, the enzymes are synthesized only in the absence of compound B. If gene $S$ is mutated, the enzymes are synthesized in the presence and in the absence of compound B. Does gene $S$ produce a repressor or an activator? Is this operon inducible or repressible?

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Key Concepts

Repressible Operons

A repressible operon is a gene cluster that is normally active but can be turned off when a particular regulatory molecule (often the end product of a biosynthetic pathway) binds to a repressor protein. This binding activates the repressor, which then binds to the operator to inhibit transcription. Such negative feedback regulation allows the cell to prevent the overaccumulation of end products and maintain metabolic balance.

Repressor Proteins

Repressor proteins are regulatory proteins that bind to specific DNA sequences (usually the operator region of an operon) to block transcription. They usually act by responding to an effector molecule, which induces a conformational change that either enables or prevents the repressor from binding to the DNA. This type of control is essential in adjusting gene expression in response to environmental or metabolic signals.

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