What are the stereochemical configurations of the two diastereomers of (2 S, 4 R)-2,4 -octanedio

What are the stereochemical configurations of the two...

Key Concepts

Diastereomers

Diastereomers are stereoisomers that are not mirror images of each other. They result when two or more stereogenic centers differ in configuration between molecules. Unlike enantiomers, diastereomers have different physical and chemical properties and are important in the context of reaction selectivity and separation techniques.

Stereogenic Centers

Stereogenic centers are atoms, usually carbons, that have four different substituents, leading to non-superimposable mirror image isomers. These centers are the focus when determining the overall stereochemistry of a molecule and play a key role in the formation of diastereomers and enantiomers.

Chirality

Chirality is a property of a molecule when it is not superimposable on its mirror image, typically because it contains one or more stereogenic centers. This concept is central to understanding how different spatial arrangements of atoms in a molecule, such as in diols, can lead to molecules with distinct physical and chemical properties.

Absolute Configuration (R/S) Notation

Absolute configuration assigns the spatial arrangement around a stereogenic center using the R (rectus) and S (sinister) system based on the Cahn-Ingold-Prelog priority rules. This notation is essential for describing the configuration of chiral centers in molecules and for distinguishing between different stereoisomers.

Transcript

00:01 So for this question, we are asked to find the two diasteremeres of the compound 2s4r 2 .4 octane dial.

00:08 And so for this question, we have to realize that we have two stereogenic centers, and therefore we are going to have two to the end stereosomers, or two to the two.

00:18 So we are going to have four stereogenic...

00:20 I'm sorry, four stereosomers.

00:24 So let me go ahead and write that down for us.

00:26 So we are going to have four stereosomers, including our...

00:31 R1 that we already have here, so our 2s4r.

00:38 So we can start by writing our 2s4r here.

00:43 And then in the previous question, we were actually asked to find the anantomir for this, and we found that it was the when the stereogenic centers were inverted.

00:52 So that would be our 2r 4s.

00:57 And so we can make a little quick note here and say that these two are anantomers.

01:10 And so that kind of leaves us with our other two stereo isomers that are going to be our diastereomers for this.

01:16 And so what we can go ahead and write them.

01:21 So that's going to be our 2r 4r and our 2s for s.

01:31 Right? and so we would say that these two are diastereomers and these two are diastomerers.

01:49 But we want to draw them out just so we can actually prove that this is the case.

01:54 So i'm not going to go and draw our an anemeteromers, but i'll go ahead and draw our diastereomers here, just to prove that they are, in fact, diastereomers.

02:03 And so what we have here is i'm going to go ahead and draw our 2s4r stereosomere, and what that's going to look like.

02:11 And so, right, of course, we're going to have our oh going away from us on both the 2 and 4.

02:21 Okay.

02:22 And so this is going to be our 2s4r...

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