00:01
What is the major product of the following reactions? a, acetophorine and nitric acid.
00:12
This reaction is nitration, and for furines, it's preferred to the alpha position.
00:31
B, bramination of nitro -fifene, also preferred to the alpha position.
00:56
Mithilation of dimethyl amino pyridine.
01:03
There are two nucleophilic centers.
01:08
However, this nuclear fiddic center is significantly deactivated by the electron withdrawing effect of nitrogen.
01:19
So the pyridine nitrogen will be methamated preferentially and after inflation, this nitrogen will be even more deactivated.
01:32
So inflation of this position is much less likely...