Question

When the action potential reaches the presynaptic terminal, which ion must enter the presynaptic terminal to evoke release of the neurotransmitter?

   When the action potential reaches the presynaptic terminal, which ion must enter the presynaptic terminal to evoke release of the neurotransmitter?

Biological Psychology

Biological Psychology

James W. Kalat 12th Edition

Chapter 2, Problem 9

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Solved by Expert Joanna Quigley

10/07/2020

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When the action potential reaches the presynaptic terminal, calcium ions (Ca2+) Show more…

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When the action potential reaches the presynaptic terminal, which ion must enter the presynaptic terminal to evoke release of the neurotransmitter?

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Key Concepts

Voltage-Gated Calcium Channels

These channels are essential in converting the electrical signal of an action potential into a chemical signal. They open in response to membrane depolarization at the presynaptic terminal, allowing calcium ions to flow into the neuron and initiate the release process.

Action Potential

An action potential is a rapid electrical signal that travels along the neuron, arriving at the presynaptic terminal. Its arrival is the key stimulus that depolarizes the terminal membrane, activating voltage-gated calcium channels and setting off neurotransmitter release.

Calcium Ion

Calcium ions (Ca2+) play a crucial role in synaptic transmission by entering the presynaptic terminal when an action potential arrives. This influx acts as a trigger for the cascade of events leading to the fusion of synaptic vesicles with the membrane and subsequent release of neurotransmitters.

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