Which of the following is true about RNAi process? (a) It is...

Name: Problem 38, Chapter 12: Objective Biology for NEET
Uploaded: 2021-11-20T09:48:35-08:00
Duration: 1 min 2 s
Channel: Hast Aggarwal
Description: Which of the following is true about RNAi process? (a) It is a method of cellular defense. (b) It involves silencing of a specific mRNA due to a complementary dsRNA molecule. (c) Source of complementary RNA in this process may be infection by viruses having RNA genomes. (d) All are true

Which of the following is true about RNAi process? (a) It is a method of cellular defense. (b) It involves silencing of a specific mRNA due to a complementary dsRNA molecule. (c) Source of complementary RNA in this process may be infection by viruses having RNA genomes. (d) All are true

Which of the following is true about RNAi process?
(a) It is a method of cellular defense.
(b) It involves silencing of a specific mRNA due to a complementary dsRNA molecule.
(c) Source of complementary RNA in this process may be infection by viruses having RNA genomes.
(d) All are true

Key Concepts

Exogenous Sources of dsRNA

Exogenous sources of dsRNA, such as viral infections, can initiate the RNAi pathway. Viruses with RNA genomes may produce dsRNA during their replication cycles, which can activate RNAi and thereby limit viral proliferation in the host cell.

Cellular Defense Mechanisms

RNA interference acts as a cellular defense mechanism by protecting cells from invasive nucleic acids such as those introduced by viral infections. It helps the immune response by recognizing and targeting foreign genetic material for degradation.

Double-Stranded RNA (dsRNA) and Complementarity

Double-stranded RNA (dsRNA) plays a crucial role in the RNAi process. It serves as a trigger for gene silencing by being processed into small interfering RNAs (siRNAs) that guide the RNA-induced silencing complex (RISC) to complementary mRNA targets, leading to their degradation.

Gene Silencing

Gene silencing refers to the regulation of gene expression, where certain genes are suppressed or turned off. In the context of RNAi, gene silencing is achieved by degrading specific mRNA molecules that correspond to the target gene, thereby inhibiting protein synthesis.

RNA interference (RNAi)

RNA interference is a conserved biological process in which double-stranded RNA (dsRNA) molecules trigger the silencing of specific genes. This process involves the degradation or suppression of mRNA molecules through sequence-specific interactions, effectively reducing or preventing the production of corresponding proteins.

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