Using the case below, pharmacology references, and what we discussed about pharmacokinetics, write a prescription for vancomycin using the appropriate dose and frequency.
Explain how you determined the vancomycin regimen.
Formulate a detailed monitoring plan including when to draw a vancomycin level (include target drug level).
Upload your document. After class on (1)/(23)/24, provide a comment within the assignment on if you would make any changes to your proposal
Patient Case:
LV is a previously healthy 32 year old who was in a motorcycle accident several weeks ago. They had an open fracture of the proximal third of the right leg as well as multiple fractures in both lower extremities. They immediately underwent surgery with reduction and external fixation of the open tibial fracture and was prophylactically treated with Augmentin (amoxicillin/clavulanic acid) for two weeks following hospital discharge. They re-presented four weeks later with increasing leg pain and fever and was diagnosed with osteomyelitis. Surgical debridement with resection of infected and necroticappearing tibial bone was performed and methicillin-resistant staphylococcus aureus (MRSA) was isolated from the OR cultures. To treat the infection, the Infectious Diseases consult service has recommended at least eight weeks of intravenous vancomycin.
VS: P 75 RR 15 Temp 99.0 BP 135/90 02 Sat
100% (RA) Weight 98kg Height 6'2"
PE: remarkable only for persistent leg pain, warmth and redness at surgical site
138,99,12
12
72
7.7
343
4.3,27.4,0.7
35.3
ESR 38m(m)/(h), CRP 8.2m(g)/(L)
Current medications:
Docusate 100mg cap q24h
Senna #1 tab q24h
Percocet (acetaminophen/oxycodone) 5mg-325mgq4-6hprn pain
PMH: Open tibial fracture
SH: +tobacco, occasional EtOH, denies illicit drugs
istructions. 1.Using the case below,pharmacology references, and what we discussed about pharmacokinetics,write a prescription for vancomycin using the appropriate dose and frequency 2. Explain how you determined the vancomycin regimen 3. Formulate a detailed monitoring plan including when to draw a vancomycin level(include target drug level) 4.Upload your document. After class on 1/23/24.provide a comment within the assignment on if you would make any changes to your proposal
Patient Case: LV is a previously healthy 32 year old who was in a motorcycle accident several weeks ago. They had an open fracture of the proximal third of the right leg as well as multiple fractures in both lower extremities. They immediately underwent surgery with reduction and external fixation of the open tibial fracture and was prophylactically treated with Augmentin (amoxicillin/clavulanic acid) for two weeks following hospital discharge. They re-presented four weeks later with increasing leg pain and fever and was diagnosed with osteomyelitis Surgical debridement with resection of infected and necrotic- appearing tibial bone was performed and methicillin-resistant staphylococcus aureus (MRSA) was isolated from the OR cultures.To treat the infection,the Infectious Diseases consult service has recommended at least eight weeks of intravenous vancomycin. VS:P 75 RR 15 Temp 99.0 BP 135/90 02 Sat 100% (RA) Weight 98 kg Height 62 PE: remarkable only for persistent leg pain, warmth and redness at surgical site 138 99 12 12 72 7.7 343 4.3 27.4 0.7 35.3 ESR 38 mm/h CRP 8.2mg/L Current medications: Docusate 100mg cap q24h Senna #1 tab q24h Percocet (acetaminophen/oxycodone) 5mg-325mg q4-6h prn pain PMH:Open tibial fracture SH:+tobacco,occasional EtOH, denies illicit drugs
