00:01
This question is asking us about drug counseling for a patient from a nurse.
00:05
This patient has a new treatment for colchicine.
00:09
Colchicine is a relatively common medication.
00:12
It's usually prescribed for gout or gouty arthritis.
00:16
That's, you know, painful inflammation of the joints for these uric acid crystals.
00:19
It can also be indicated for various heart conditions.
00:25
It's an anti -inflammatory.
00:26
It has some effects like in cardiovascular health, both chronic and long -term and short -term.
00:33
So colchicine prescriptions can come in two different forms.
00:36
You can get either sort of a low dose, like kind of chronic, taking a little bit for preventative care, or you can get quite a high dose amount in the middle of like a gout attack for an acute attack.
00:55
Attack.
00:55
So two different ways that colchicine can be prescribed.
00:59
It's usually prescribed orally.
01:00
It's absorbed orally.
01:02
But note that this drug, colchicine, has a really low, has a really small therapeutic index.
01:11
Therapeutic index is a way that we just talk about the difference between the drug's effectiveness and its toxicity.
01:16
So there's quite a narrow window here where you can get the drug at the dose where it's actually going to help before the drug, the dose at which it becomes really dangerous, can cause like multiple organ failure.
01:25
So we definitely want to look for side effects here...