At the neuromuscular junction, the arrival of an action potential at the axon terminal causes...to open. voltage-gated Ca2+ channels voltage-gated Na+ channels leakage channels for K+ chemically-gated Ca2+ channels chemically-gated Na+ channels
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This allows Ca2+ to flow into the cell, triggering the release of neurotransmitters into the synaptic cleft. Show more…
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Which of the following is an example of a chemically-gated channel? 1) potassium channels in action potentials 2) sodium channels in action potentials 3) calcium channels in axon terminals 4) cholinergic nicotinic receptor
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A neurophysiology expert is teaching his students the physiology of the neuromuscular junction. While describing the sequence of events that takes place at the neuromuscular junction, he mentions that as the action potential travels down the motor neuron, it produces depolarization of the presynaptic membrane. This results in the opening of voltage-gated calcium channels, which leads to the release of calcium ions into the synaptic cleft. The binding of calcium ions to nicotinic acetylcholine receptors on the motor end plate causes an increased conductance of sodium and potassium ions. Additionally, calcium ions bind to vesicles containing acetylcholine, leading to exocytosis of acetylcholine into the synaptic cleft. This process ultimately results in the generation of an end plate potential.
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