00:01
In this question, we have been asked that a dash mutation in a receptor codon would not prevent the normal function.
00:10
Option a says silent mutation.
00:14
So, in this basically the codon is changed such that the codon is changed to a synonymous codon and therefore there will be the same amino acid that is formed.
00:27
Then option b says missense mutation.
00:32
So, here basically one of the codon, one of the nucleotide chain brings about the different amino acid and due to which the property of the protein will be changed.
00:47
Then option c says nonsense mutation.
00:50
So, here basically the nucleotide chain brings in the top codon and due to which there will be truncated protein.
00:58
Then option d says deletion.
01:00
So, here also the codon will be changed in a way that different amino acid sequence will be there.
01:06
So, it is only the silent mutation which will not prevent its normal function.
01:12
So, i write the answer here will be option a that is silent mutation.
01:17
Then in the next question it says from the following statement choose the most likely effect of deleting two nucleotides in a codon at a receptor binding site.
01:27
So, option a says the reading frame would be changed producing a non -functional receptor.
01:34
So, here basically if there is deletion then surely the reading frame will be changed and due to which there will be change in the amino acid sequence.
01:46
So, due to which there can be many changes like it will not be able to bind to the ligand or it can lead to a non -functional receptor depending on what change is there.
01:58
So, this here is true.
02:00
Then option b says that changing an amino acid in the binding site will cause ligand to no longer be compatible with the receptor...