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3. Sickle-cell anemia is an interesting human genetic disease. Normal homozygous individuals (SS) have normal blood cells that are easily infected with the malarial parasite. Many of these individuals become very ill from the parasite and many die. Individuals homozygous for the sickle-cell trait (ss) have red blood cells where malaria cannot grow; however, their red blood cells readily collapse when deoxygenated and these individuals often die because of this genetic defect. Individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause mortality. However, malaria cannot survive well within these "partially defective" red blood cells. Thus, heterozygotes tend to survive better than either of the homozygous conditions. If 16% of an African population is born with a severe form of sickle-cell anemia (ss), predict what percentage of the population will be more resistant to malaria because they are heterozygous (Ss) for the sickle-cell gene.

          3. Sickle-cell anemia is an interesting human genetic disease. Normal homozygous individuals (SS) have normal blood cells that are easily infected with the malarial parasite. Many of these individuals become very ill from the parasite and many die. Individuals homozygous for the sickle-cell trait (ss) have red blood cells where malaria cannot grow; however, their red blood cells readily collapse when deoxygenated and these individuals often die because of this genetic defect. Individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause mortality. However, malaria cannot survive well within these "partially defective" red blood cells. Thus, heterozygotes tend to survive better than either of the homozygous conditions. If 16% of an African population is born with a severe form of sickle-cell anemia (ss), predict what percentage of the population will be more resistant to malaria because they are heterozygous (Ss) for the sickle-cell gene.

3. Sickle-cell anemia is an interesting human genetic disease. Normal homozygous individuals (SS) have normal blood cells that are easily infected with the malarial parasite. Many of these individuals become very ill from the parasite and many die. Individuals homozygous for the sickle-cell trait (ss) have red blood cells where malaria cannot grow; however, their red blood cells readily collapse when deoxygenated and these individuals often die because of this genetic defect. Individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause mortality. However, malaria cannot survive well within these "partially defective" red blood cells. Thus, heterozygotes tend to survive better than either of the homozygous conditions. If 16% of an African population is born with a severe form of sickle-cell anemia (ss), predict what percentage of the population will be more resistant to malaria because they are heterozygous (Ss) for the sickle-cell gene.

Added by Holly W.

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