Question

5) Direct methylation of DNA (as opposed to histone methylation, which is something else) is an important mechanism of eukaryotic gene regulation. DNA methylation primarily occurs at specific bases. a. Given the DNA sequence below, fill in the bubbles over the specific individual bases which you expect to be methylated: 5' A T G T G C A C G T T T A T G T G A C C G T A A 3' b. If the promoter region for a gene is heavily methylated, do you expect this will increase or decrease expression relative to being unmethylated? Increased expression Decreased expression c. Explain why.

          5) Direct methylation of DNA (as opposed to histone methylation, which is something else) is an important mechanism of eukaryotic gene regulation. DNA methylation primarily occurs at specific bases.
a. Given the DNA sequence below, fill in the bubbles over the specific individual bases which you expect to be methylated:
5' A T G T G C A C G T T T A T G T G A C C G T A A 3'
b. If the promoter region for a gene is heavily methylated, do you expect this will increase or decrease expression relative to being unmethylated?
Increased expression
Decreased expression
c. Explain why.

5) Direct methylation of DNA (as opposed to histone methylation, which is something else) is an important mechanism of eukaryotic gene regulation. DNA methylation primarily occurs at specific bases.
a. Given the DNA sequence below, fill in the bubbles over the specific individual bases which you expect to be methylated:
5' A T G T G C A C G T T T A T G T G A C C G T A A 3'
b. If the promoter region for a gene is heavily methylated, do you expect this will increase or decrease expression relative to being unmethylated?
Increased expression
Decreased expression
c. Explain why.

Added by Javier M.

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