DNA adenine large, energy dependent multi-subunit complexes RNA HDACs cytosine SWI/SNF complexes HATs H2A regulatory proteins transcription factors and RNA polymerase H2A.Z thymine increase(s) decrease(s) guanine DNA methylation has been linked to a [ ] in gene expression. It most often occurs at position 5 of [ ]. Histone acetylation [ ] the positive charge on histones, resulting in a reduced affinity of the histone for [ ]. The process is catalyzed by [ ] and results in forming "open" chromatin. Chromatin remodeling leaves DNA open to associate with [ ] by repositioning or removing nucleosomes using [ ]. One way in which nucleosomes can be modified is by changing their composition. Histone variants, like [ ], affect nucleosome mobility and positioning on [ ].
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What effect does DNA methylation have on gene expression? It increases it. It decreases it. It depends on which base is methylated. DNA methylation has no effect on gene expression. Increased mRNA stability should have what effect on the levels of the corresponding protein in a cell? Higher protein levels. Lower protein levels. mRNA stability does not affect protein levels. It depends on the cell type. What class of enzymes generally open up chromatin to increase gene expression? Histone acetyltransferases. Histone deacetylases. DNA methyltransferase. Heterochromatin protein. Which type of transcription factor binds both RNA polymerase and general transcription factors? Histone acetyltransferase. Repressor. Activator. Heterochromatin protein. The regulation of most gene expression occurs at the level of transcription initiation. Chromatin structure. Translation initiation. mRNA stability.
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