What effect does DNA methylation have on gene expression? A. It increases it B. It decreases it C. It depends of which base is methylated D. DNA methylation has no effect on gene expression Increased mRNA stability should have what effect on the levels of the corresponding protein in a cell? A. Higher protein levels B. Lower protein levels C. mRNA stability does not affect protein levels D. It depends on the cell type What class of enzymes generally open up chromatin to increase gene expression? A. Histone acetyltransferases B. Histone deacetylases C. DNA methyltransferase D. Heterochromatin protein 1 Which type of transcription factor binds both RNA polymerase and general transcription factors? A. Histone acetyltransferase B. Repressor C. Activator D. Heterochromatin protein 1 In bacteria, the regulation of most gene expression occurs at the level of A. Transcription initiation B. Chromatin structure C. Translation initiation D. mRNA stability
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DNA methylation has been linked to gene expression. Histone acetylation is a positive charge that is catalyzed by histones, resulting in reduced affinity of the histone and resulting in the formation of open chromatin. Chromatin remodeling leaves DNA open to associate with nucleosomes by repositioning or removing them. One way in which nucleosomes can be modified is by changing their composition, such as histone variants, which can affect nucleosome mobility and positioning.
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