33. During initiation of translation, a. the initiator tRNAmet binds to the A site of a ribosome. b. specific rRNA base pairs with a sequence in mRNA to position a ribosome at the start codon. c. IF-3 must be recruited to the 30S ribosome in order for the 70S initiation complex to assemble. d. there is no energy expenditure as the tRNA binding to mRNA is via complementary base pairing. e. Both 70S and 30S ribosome subunits must simultaneously recognize an mRNA to bind.
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Adi S.
Transfer RNA (tRNA) is important in translation because it forms the structural framework in ribosomes to which ribosomal proteins attach. It is an adaptor molecule that can bind both amino acids and mRNA. It acts as an initiation factor (IF) in translation. It is found in the nucleus.
Below are the major steps involved in the initiation of translation in eukaryotes. Put them in the correct order: 1. Initiator tRNA and translation initiation factors bind to the small ribosomal subunit. 2. Small ribosomal subunit binds to mRNA. 3. Ribosomal subunit/tRNA initiation factor complex scans the mRNA for the first AUG. 4. Charged tRNA enters the A site of the ribosome. 5. Peptide bond forms between methionine and the next amino acid. 6. Large ribosomal subunit binds. 7. Translation initiation factors dissociate.
Dr. Anas S.
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