6) The error-prone pathway results from misincorporation of nucleotides opposite a site of unrepaired damage using specialized DNA polymerases. One of these tends to incorporate an adenine nucleotide opposite a pyrimidine dimer. Is this a good strategy for dealing with UV damage? Calculate the frequency of base changes using adenine insertion versus random incorporation for E. coli, where pyrimidine dimers are approximately 60% TT, 30% TC and CT, and 10% CC. (4 points)
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coli - TT dimers: 60% - TC dimers: 30% - CT dimers: 30% - CC dimers: 10% Show more…
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